HitPredict

Interactor 1: CSN5 (Q92905)
COP9 signalosome complex subunit 5 (SGN5) (Signalosome subunit 5) (EC 3.4.-.-) (Jun activation domain-binding protein 1)
Gene: COPS5

Interactor 2: KLDC3 (Q9BQ90)
Kelch domain-containing protein 3 (Testis intracellular mediator protein)
Gene: KLHDC3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 334 Hs			1 382
+	Hs
		320835 CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00		KLH18_HUMAN (2-284): 1.33e-54: 190: 19.44
+	Hs
		1370428 CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00		KLH13_HUMAN (140-381): 4.88e-40: 152: 14.98
+	Hs
		1199010 CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00		KLH12_HUMAN (1-191): 2.58e-39: 149: 18.33
+	Hs
		1235379 CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00		KLH10_HUMAN (2-190): 2.7e-32: 129: 17.46
+	Hs
		1370426 CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00		KLHL9_HUMAN (1-188): 4.93e-31: 126: 14.58
+	Hs
		1370358 CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00		KLHL4_HUMAN (249-381): 4.27e-22: 100: 13.53
+	Hs
		1370425 CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00		KLHL8_HUMAN (1-136): 1.73e-20: 95.1: 19.12
+	Hs
		296371 CSN5_HUMAN (1-334): 6.67e-131: 378: 100.00		ATRN_HUMAN (4-108): 2.08e-09: 61.6: 23.85
+	Hs
		131538 EIF3F_HUMAN (44-328): 3.26e-64: 208: 14.48		KLH20_HUMAN (188-382): 1.21e-40: 153: 10.26