HitPredict

Interactor 1: UB2E3 (Q969T4)
Ubiquitin-conjugating enzyme E2 E3 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme E3) (UbcH9) (Ubiquitin carrier protein E3) (Ubiquitin-conjugating enzyme E2-23 kDa) (Ubiquitin-protein ligase E3)
Gene: UBE2E3

Interactor 2: RNF11 (Q9Y3C5)
RING finger protein 11
Gene: RNF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	19549727, 32814053
Identification Methods	two hybrid, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 207 Hs			1 154
+	Hs
		1397305 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		RNF11_HUMAN (1-154): 3.84e-43: 141: 100.00
+	Hs
		1490987 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		RNF11_HUMAN (1-154): 3.84e-43: 141: 100.00
+	Hs
		220513 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		RNF13_HUMAN (77-146): 8.83e-27: 104: 33.80
+	Hs
		1294227 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		GOLI_HUMAN (64-146): 5.88e-26: 103: 25.30
+	Hs
		1381223 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		RN115_HUMAN (10-154): 1.54e-26: 103: 19.08
+	Hs
		1397307 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		RN115_HUMAN (10-154): 1.54e-26: 103: 19.08
+	Hs
		1381219 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		RN150_HUMAN (57-146): 1.03e-24: 99: 26.67
+	Hs
		1397296 UB2E2_HUMAN (1-207): 8.61e-89: 261: 85.02		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		1381201 UB2E3_HUMAN (1-207): 9.59e-90: 263: 100.00		RN167_HUMAN (77-143): 4.98e-21: 89.1: 36.77
+	Hs
		220521 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		RNF13_HUMAN (77-146): 8.83e-27: 104: 33.80
+	Hs
		1294294 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		GOLI_HUMAN (64-146): 5.88e-26: 103: 25.30
+	Hs
		1490989 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		RN115_HUMAN (10-154): 1.54e-26: 103: 19.08
+	Hs
		220490 UB2D2_HUMAN (61-206): 1.33e-82: 243: 65.07		RNF13_HUMAN (77-146): 8.83e-27: 104: 33.80
+	Hs
		982231 UB2D2_HUMAN (61-206): 1.33e-82: 243: 65.07		GOLI_HUMAN (64-146): 5.88e-26: 103: 25.30
+	Hs
		982249 UB2D2_HUMAN (61-206): 1.33e-82: 243: 65.07		RN149_HUMAN (66-147): 1.16e-25: 102: 35.37
+	Hs
		1461632 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		RN150_HUMAN (57-146): 1.03e-24: 99: 26.67
+	Hs
		982225 UB2D2_HUMAN (61-206): 1.33e-82: 243: 65.07		SYVN1_HUMAN (72-152): 1.78e-24: 99: 28.40
+	Hs
		1450919 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		1435277 UB2D4_HUMAN (61-206): 6.38e-83: 244: 63.01		RN167_HUMAN (77-143): 4.98e-21: 89.1: 36.77
+	Hs
		982322 UB2D2_HUMAN (61-206): 1.33e-82: 243: 65.07		RN167_HUMAN (77-143): 4.98e-21: 89.1: 36.77