HitPredict

Interactor 1: VATE2 (Q96A05)
V-type proton ATPase subunit E 2 (V-ATPase subunit E 2) (Vacuolar proton pump subunit E 2)
Gene: ATP6V1E2

Interactor 2: VPP2 (Q9Y487)
V-type proton ATPase 116 kDa subunit a 2 (V-ATPase 116 kDa subunit a 2) (Lysosomal H(+)-transporting ATPase V0 subunit a 2) (TJ6) (Vacuolar proton translocating ATPase 116 kDa subunit a isoform 2)
Gene: ATP6V0A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	V_ATPase_I~vATP-synt_E
Common GO terms	GO:0001669 - acrosomal vesicle GO:0016241 - regulation of macroautophagy GO:0046961 - proton-transporting ATPase activity, rotational mechanism
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 226 Hs			1 856
+	Hs
		784815 VATE1_HUMAN (1-225): 3.67e-98: 286: 76.89		VPP2_HUMAN (1-856): 0: 1321: 100.00
+	Hs
		784800 VATE1_HUMAN (1-225): 3.67e-98: 286: 76.89		VPP1_HUMAN (1-842): 0: 1278: 53.19
+	Hs
		1371944 VATE2_HUMAN (1-226): 5.43e-90: 266: 100.00		VPP1_HUMAN (1-842): 0: 1278: 53.19
+	Hs
		784807 VATE1_HUMAN (1-225): 3.67e-98: 286: 76.89		VPP4_HUMAN (1-843): 0: 1227: 51.89
+	Hs
		1381837 VATE2_HUMAN (1-226): 5.43e-90: 266: 100.00		VPP4_HUMAN (1-843): 0: 1227: 51.89
+	Hs
		784787 VATE1_HUMAN (1-225): 3.67e-98: 286: 76.89		VPP3_HUMAN (1-843): 0: 1082: 49.35
+	Sc
		645806 VATE_YEAST (2-225): 2.39e-76: 231: 35.40		VPP1_YEAST (3-842): 0: 1037: 36.46
+	Sc
		645813 VATE_YEAST (2-225): 2.39e-76: 231: 35.40		VPP2_YEAST (3-845): 0: 947: 33.19