HitPredict

Interactor 1: SPSB4 (Q96A44)
SPRY domain-containing SOCS box protein 4 (SSB-4)
Gene: SPSB4

Interactor 2: RBX2 (Q9UBF6)
RING-box protein 2 (Rbx2) (EC 2.3.2.27) (EC 2.3.2.32) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)
Gene: RNF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.62 0.60 0.611

The method score is based on:

Property Details
Experiments 28931592, 15601820
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0016567 - protein ubiquitination
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 273
Hs

1 113
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Service provided by Combinatics, Japan

Last updated: 11Aug2025