HitPredict

Interactor 1: ARL8A (Q96BM9)
ADP-ribosylation factor-like protein 8A (ADP-ribosylation factor-like protein 10B) (Novel small G protein indispensable for equal chromosome segregation 2)
Gene: ARL8A

Interactor 2: PKHA4 (Q9H4M7)
Pleckstrin homology domain-containing family A member 4 (PH domain-containing family A member 4) (Phosphoinositol 3-phosphate-binding protein 1) (PEPP-1)
Gene: PLEKHA4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31091453
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arf~PH
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 186 Hs			1 779
+	Hs
		975244 ARF6_HUMAN (12-183): 1.04e-86: 253: 33.72		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		1015123 ARF5_HUMAN (11-184): 3.49e-86: 252: 29.89		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		981362 RAB1A_HUMAN (5-185): 2.8e-70: 213: 22.16		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		1430474 RAB1B_HUMAN (21-185): 1.96e-69: 211: 23.67		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		1014963 ARF1_HUMAN (1-185): 8.87e-65: 198: 30.81		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		958820 ARF3_HUMAN (1-185): 8.22e-65: 198: 30.27		PKHA4_HUMAN (1-779): 1.18e-148: 455: 100.00
+	Hs
		975059 ARF6_HUMAN (12-183): 1.04e-86: 253: 33.72		DGKD_HUMAN (34-677): 4.41e-46: 180: 13.91
+	Hs
		975256 ARF6_HUMAN (12-183): 1.04e-86: 253: 33.72		PKHA1_HUMAN (3-261): 4.01e-41: 157: 17.49
+	Hs
		975254 ARF6_HUMAN (12-183): 1.04e-86: 253: 33.72		PKHA5_HUMAN (114-732): 4.97e-38: 154: 17.22
+	Hs
		975077 ARF6_HUMAN (12-183): 1.04e-86: 253: 33.72		RHG21_HUMAN (12-723): 2.27e-35: 147: 13.40
+	Hs
		1015040 ARF5_HUMAN (11-184): 3.49e-86: 252: 29.89		RHG21_HUMAN (12-723): 2.27e-35: 147: 13.40
+	Hs
		975093 ARF6_HUMAN (12-183): 1.04e-86: 253: 33.72		PKHA7_HUMAN (153-638): 3.81e-34: 143: 23.37
+	Hs
		1229841 ARL8A_HUMAN (1-186): 5.36e-69: 209: 100.00		CYTSA_HUMAN (176-644): 5.29e-44: 173: 10.59
+	Hs
		975339 ARF6_HUMAN (12-183): 1.04e-86: 253: 33.72		FARP1_HUMAN (6-166): 1.24e-24: 112: 18.07
+	Hs
		1430476 RAB1B_HUMAN (21-185): 1.96e-69: 211: 23.67		PKHA2_HUMAN (37-252): 6.2e-39: 151: 20.50
+	Mm
		1014990 ARF1_MOUSE (1-185): 8.87e-65: 198: 30.81		RHG21_MOUSE (12-677): 9.14e-37: 151: 13.96
+	Hs
		1014904 ARF1_HUMAN (1-185): 8.87e-65: 198: 30.81		RHG21_HUMAN (12-723): 2.27e-35: 147: 13.40
+	Hs
		958779 ARF3_HUMAN (1-185): 8.22e-65: 198: 30.27		RHG21_HUMAN (12-723): 2.27e-35: 147: 13.40