HitPredict

Interactor 1: IMA4 (O00505)
Importin subunit alpha-4 (Importin alpha Q2) (Qip2) (Karyopherin subunit alpha-3) (SRP1-gamma)
Gene: KPNA3

Interactor 2: NFKB1 (P19838)
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene: NFKB1

Species: Homo sapiens

Source: dip

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	1.00	0.665

Property	Details
Experiments	14743216
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~Arm
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 521 Hs			1 968
+	Hs
		626130 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		NFKB1_HUMAN (1-968): 0: 761: 100.00
+	Hs
		138670 IMA4_HUMAN (1-521): 1.86e-160: 468: 100.00		TF65_HUMAN (28-428): 3.14e-109: 350: 34.07
+	Hs
		142533 IMA3_HUMAN (1-521): 3.11e-157: 459: 85.80		TF65_HUMAN (28-428): 3.14e-109: 350: 34.07
+	Hs
		910855 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		RELB_HUMAN (30-443): 3.55e-117: 372: 34.37
+	Hs
		253611 IMA7_HUMAN (4-520): 7.74e-139: 413: 46.43		RELB_HUMAN (30-443): 3.55e-117: 372: 34.37
+	Hs
		910860 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		TF65_HUMAN (28-428): 3.14e-109: 350: 34.07
+	Hs
		911215 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		RELB_HUMAN (30-443): 3.55e-117: 372: 34.37
+	Hs
		253612 IMA7_HUMAN (4-520): 7.74e-139: 413: 46.43		TF65_HUMAN (28-428): 3.14e-109: 350: 34.07
+	Hs
		911217 IMA5_HUMAN (5-520): 9.79e-132: 395: 45.52		TF65_HUMAN (28-428): 3.14e-109: 350: 34.07
+	Hs
		910919 IMA1_HUMAN (3-521): 3.15e-142: 421: 48.67		IKBB_HUMAN (541-743): 4.61e-20: 95.1: 32.39