HitPredict

Interactor 1: P2C77 (O04719)
Protein phosphatase 2C 77 (AtPP2C77) (EC 3.1.3.16) (Protein ABSCISIC ACID-INSENSITIVE 2) (Protein phosphatase 2C ABI2) (PP2C ABI2)
Gene: ABI2

Interactor 2: PYL8 (Q9FGM1)
Abscisic acid receptor PYL8 (ABI1-binding protein 1) (PYR1-like protein 8) (Regulatory components of ABA receptor 3)
Gene: PYL8

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	1.00	0.896

Property	Details
Experiments	19769575, 32612234, 23370718, unassigned2354
Identification Methods	two hybrid, protein complementation assay, affinity chromatography technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PP2C~Polyketide_cyc2
Common GO terms	GO:0005634 - nucleus GO:0009737 - response to abscisic acid GO:0009738 - abscisic acid-activated signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 423 At			1 188
+	At
		138635 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL9_ARATH (17-185): 7.35e-100: 288: 76.92
+	At
		138636 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL10_ARATH (15-182): 4.99e-88: 257: 76.92
+	At
		138616 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYR1_ARATH (13-179): 1.84e-85: 251: 46.15
+	At
		138619 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL2_ARATH (5-182): 1.63e-82: 244: 42.62
+	At
		138648 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL5_ARATH (17-178): 6.31e-80: 237: 51.22
+	At
		829518 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL8_ARATH (1-188): 4.51e-107: 306: 100.00
+	At
		138637 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL6_ARATH (17-179): 1.27e-77: 232: 47.31
+	At
		138618 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL4_ARATH (20-182): 4.62e-77: 231: 53.33
+	At
		138654 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL3_ARATH (15-175): 2.27e-74: 224: 41.86
+	At
		138639 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL1_ARATH (14-178): 1.26e-72: 220: 46.47
+	At
		829503 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL9_ARATH (17-185): 7.35e-100: 288: 76.92
+	At
		829492 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL7_ARATH (16-186): 8.73e-98: 283: 73.68
+	At
		138647 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL11_ARATH (30-179): 2.45e-64: 197: 51.32
+	At
		829504 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL10_ARATH (15-182): 4.99e-88: 257: 76.92
+	At
		221991 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYR1_ARATH (13-179): 1.84e-85: 251: 46.15
+	At
		138653 P2C77_ARATH (1-423): 1.96e-171: 488: 100.00		PYL13_ARATH (31-178): 4.5e-57: 178: 41.29
+	At
		286072 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL2_ARATH (5-182): 1.63e-82: 244: 42.62
+	At
		829507 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL6_ARATH (17-179): 1.27e-77: 232: 47.31
+	At
		285957 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL4_ARATH (20-182): 4.62e-77: 231: 53.33
+	At
		829510 P2C56_ARATH (1-423): 5.72e-144: 418: 70.52		PYL1_ARATH (14-178): 1.26e-72: 220: 46.47