HitPredict

Interactor 1: PDLI5 (Q96HC4)
PDZ and LIM domain protein 5 (Enigma homolog) (Enigma-like PDZ and LIM domains protein)
Gene: PDLIM5

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 596 Hs			1 1620
+	Hs
		878583 PAXI_HUMAN (96-534): 1.78e-34: 140: 13.90		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		412432 PDLI5_HUMAN (1-596): 1.41e-126: 386: 100.00		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		464064 PDLI7_HUMAN (257-594): 6.85e-30: 125: 15.68		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		464073 TES_HUMAN (472-595): 1.28e-23: 105: 22.54		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		840935 PAXI_HUMAN (96-534): 1.78e-34: 140: 13.90		ABL2_HUMAN (1103-1526): 1.43e-118: 405: 32.47
+	Hs
		465453 PAXI_HUMAN (96-534): 1.78e-34: 140: 13.90		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Mm
		1354129 PAXI_MOUSE (96-534): 8.61e-37: 146: 14.81		FAK2_MOUSE (1061-1496): 1.35e-110: 378: 28.31
+	Hs
		439856 PDLI7_HUMAN (257-594): 6.85e-30: 125: 15.68		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		650176 TRIP6_HUMAN (87-542): 2.33e-28: 120: 14.26		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		878458 PAXI_HUMAN (96-534): 1.78e-34: 140: 13.90		FAK2_HUMAN (1054-1518): 3.57e-109: 374: 27.45
+	Hs
		212726 TGFI1_HUMAN (93-535): 5.54e-31: 128: 12.50		FAK2_HUMAN (1054-1518): 3.57e-109: 374: 27.45
+	Hs
		253952 LPXN_HUMAN (164-535): 1.14e-30: 125: 17.20		FAK2_HUMAN (1054-1518): 3.57e-109: 374: 27.45
+	Mm
		1408915 LPXN_MOUSE (159-536): 5.38e-27: 114: 14.82		FAK2_MOUSE (1061-1496): 1.35e-110: 378: 28.31
+	Hs
		465681 TES_HUMAN (472-595): 1.28e-23: 105: 22.54		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		650157 FHL3_HUMAN (393-472): 9.53e-10: 61.8: 22.47		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		541625 LPP_HUMAN (132-590): 1.6e-53: 194: 16.25		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		1151518 TRIP6_HUMAN (87-542): 2.33e-28: 120: 14.26		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		1157102 LIMD1_HUMAN (73-533): 2.42e-22: 103: 14.37		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03