HitPredict

Interactor 1: TCPE (P48643)
T-complex protein 1 subunit epsilon (TCP-1-epsilon) (EC 3.6.1.-) (CCT-epsilon) (Chaperonin containing T-complex polypeptide 1 subunit 5)
Gene: CCT5

Interactor 2: THOC3 (Q96J01)
THO complex subunit 3 (Tho3) (TEX1 homolog) (hTREX45)
Gene: THOC3

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.50	0.609

Property	Details
Experiments	28514442, 33961781, 37500615
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 541 Hs			1 351
+	Hs
		876081 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1B_HUMAN (85-349): 4.29e-83: 261: 20.45
+	Hs
		875898 TCPE_HUMAN (1-541): 0: 637: 100.00		WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75
+	Hs
		882090 TCPG_HUMAN (14-540): 0: 574: 33.15		THOC3_HUMAN (1-351): 6.57e-88: 269: 100.00
+	Hs
		1394575 TCPH_HUMAN (12-539): 0: 572: 29.64		THOC3_HUMAN (1-351): 6.57e-88: 269: 100.00
+	Hs
		882051 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1B_HUMAN (85-349): 4.29e-83: 261: 20.45
+	Hs
		882014 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52
+	Hs
		1291941 TCPH_HUMAN (12-539): 0: 572: 29.64		WDR5B_HUMAN (84-350): 1.27e-81: 253: 17.52
+	Hs
		881861 TCPG_HUMAN (14-540): 0: 574: 33.15		WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75
+	Hs
		965190 TCPH_HUMAN (12-539): 0: 572: 29.64		WDR5_HUMAN (4-251): 1.22e-70: 225: 18.75
+	Hs
		876199 TCPE_HUMAN (1-541): 0: 637: 100.00		NLE1_HUMAN (215-351): 1.09e-40: 150: 22.22
+	Hs
		876070 TCPE_HUMAN (1-541): 0: 637: 100.00		POC1A_HUMAN (4-168): 2.05e-40: 148: 19.28
+	Hs
		876112 TCPE_HUMAN (1-541): 0: 637: 100.00		SNR40_HUMAN (1-122): 1.69e-19: 90.1: 19.85
+	Hs
		882038 TCPG_HUMAN (14-540): 0: 574: 33.15		POC1A_HUMAN (4-168): 2.05e-40: 148: 19.28
+	Hs
		1334162 TCPH_HUMAN (12-539): 0: 572: 29.64		POC1A_HUMAN (4-168): 2.05e-40: 148: 19.28
+	Hs
		876151 TCPE_HUMAN (1-541): 0: 637: 100.00		KTNB1_HUMAN (47-287): 1.48e-12: 70.5: 24.50
+	Hs
		876146 TCPE_HUMAN (1-541): 0: 637: 100.00		TBL1Y_HUMAN (2-84): 1.2e-09: 61.6: 13.25
+	Hs
		845257 TCPG_HUMAN (14-540): 0: 574: 33.15		LIS1_HUMAN (262-351): 1.75e-20: 93.5: 20.88
+	Hs
		882075 TCPG_HUMAN (14-540): 0: 574: 33.15		FBXW7_HUMAN (251-351): 1.11e-17: 86.2: 15.53
+	Hs
		882119 TCPG_HUMAN (14-540): 0: 574: 33.15		TBL1Y_HUMAN (2-84): 1.2e-09: 61.6: 13.25
+	Hs
		1407533 TCPH_HUMAN (12-539): 0: 572: 29.64		TBL1Y_HUMAN (2-84): 1.2e-09: 61.6: 13.25