HitPredict

Interactor 1: ASPP1 (Q96KQ4)
Apoptosis-stimulating of p53 protein 1 (Protein phosphatase 1 regulatory subunit 13B)
Gene: PPP1R13B

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38280479
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1090 Hs			1 400
+	Hs
		1115607 ASPP2_HUMAN (1-1090): 4.97e-143: 460: 45.93		WWTR1_HUMAN (1-400): 5.18e-126: 371: 100.00
+	Hs
		862111 ASPP2_HUMAN (1-1090): 4.97e-143: 460: 45.93		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		132239 ASPP1_HUMAN (1-1090): 2.12e-152: 484: 100.00		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46
+	Hs
		1115588 ASPP2_HUMAN (1-1090): 4.97e-143: 460: 45.93		ITCH_HUMAN (37-356): 2.66e-60: 211: 14.83
+	Hs
		132021 ASPP2_HUMAN (1-1090): 4.97e-143: 460: 45.93		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46
+	Hs
		862319 DOT1L_HUMAN (94-844): 1.6e-73: 269: 16.71		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		920503 DAPK1_HUMAN (768-1075): 9.91e-50: 195: 13.83		WWTR1_HUMAN (1-400): 5.18e-126: 371: 100.00
+	Hs
		861599 ASPP2_HUMAN (1-1090): 4.97e-143: 460: 45.93		NEDD4_HUMAN (109-352): 7.43e-23: 103: 11.00
+	Hs
		1311399 ANKH1_HUMAN (834-987): 8.88e-20: 98.3: 19.28		WWTR1_HUMAN (1-400): 5.18e-126: 371: 100.00
+	Hs
		171322 MYPT1_HUMAN (821-1021): 1.29e-14: 81.1: 24.27		WWTR1_HUMAN (1-400): 5.18e-126: 371: 100.00
+	Hs
		861581 Q05BL1_HUMAN (89-1090): 4.14e-102: 347: 44.27		NEDD4_HUMAN (109-352): 7.43e-23: 103: 11.00
+	Dm
		1489771 Q9W2J2_DROME (126-1085): 8.27e-68: 249: 26.94		Q9W2L2_DROME (11-209): 8.89e-41: 156: 17.59
+	Hs
		132166 ANR44_HUMAN (754-1080): 6.5e-51: 197: 14.62		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46
+	Hs
		171197 MYPT1_HUMAN (821-1021): 1.29e-14: 81.1: 24.27		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		295469 PSD10_HUMAN (962-1090): 2.12e-15: 78.7: 15.79		YAP1_HUMAN (14-400): 3.69e-97: 300: 41.13
+	Hs
		1206146 TGO1_HUMAN (10-584): 5.67e-52: 202: 16.51		SAV1_HUMAN (2-252): 3.59e-48: 169: 15.89
+	Hs
		1439007 ANR50_HUMAN (723-979): 3.96e-35: 148: 14.01		SMUF1_HUMAN (55-362): 3.98e-51: 184: 16.62
+	Hs
		1206164 TGO1_HUMAN (10-584): 5.67e-52: 202: 16.51		WWOX_HUMAN (111-236): 1.79e-18: 88.4: 21.09
+	Hs
		131630 PSD10_HUMAN (962-1090): 2.12e-15: 78.7: 15.79		WWP2_HUMAN (3-220): 6.69e-59: 207: 19.46