HitPredict

Interactor 1: MTMR9 (Q96QG7)
Myotubularin-related protein 9 (Inactive phosphatidylinositol 3-phosphatase 9)
Gene: MTMR9

Interactor 2: MTMR7 (Q9Y216)
Phosphatidylinositol-3-phosphate phosphatase MTMR7 (EC 3.1.3.64) (Inositol 1,3-bisphosphate phosphatase) (Myotubularin-related protein 7)
Gene: MTMR7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.96	1.00	0.982

Property	Details
Experiments	27880917, 28514442, 12890864, 25659891, 29892012, 25416956, 32296183, 33961781, 31515488, unassigned1304, unassigned3799
Identification Methods	affinity chromatography technology, pull down, two hybrid, two hybrid prey pooling approach, two hybrid array, anti tag coimmunoprecipitation, validated two hybrid
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	Myotub-related~Myotub-related
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0046856 - phosphatidylinositol dephosphorylation
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 549 Hs			1 660
+	Hs
		1388923 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR8_HUMAN (1-638): 0: 771: 54.62
+	Hs
		1400893 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR6_HUMAN (1-594): 0: 733: 58.33
+	Hs
		1112380 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR1_HUMAN (2-566): 0: 719: 34.21
+	Hs
		1112416 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR2_HUMAN (2-545): 0: 703: 36.89
+	Hs
		1388921 MTMR8_HUMAN (5-542): 0: 698: 34.06		MTMR8_HUMAN (1-638): 0: 771: 54.62
+	Hs
		1112357 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMR1_HUMAN (2-566): 0: 719: 34.21
+	Hs
		1112403 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMR2_HUMAN (2-545): 0: 703: 36.89
+	Hs
		1400887 MTMR9_HUMAN (1-549): 0: 769: 100.00		MTMR9_HUMAN (2-547): 0: 645: 35.69
+	Hs
		1107649 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTM1_HUMAN (10-568): 0: 686: 35.25
+	Hs
		1112425 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMRA_HUMAN (9-475): 2.91e-147: 448: 20.88
+	Hs
		1112409 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMRD_HUMAN (134-654): 1.07e-127: 416: 21.93
+	Hs
		1112420 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMRC_HUMAN (12-475): 1.57e-135: 416: 23.09
+	Hs
		1112371 MTMR1_HUMAN (5-539): 0: 712: 35.53		MTMRD_HUMAN (134-654): 1.07e-127: 416: 21.93
+	Hs
		331751 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMR5_HUMAN (133-615): 1.75e-112: 374: 22.92
+	Hs
		331750 MTMR1_HUMAN (5-539): 0: 712: 35.53		MTMR5_HUMAN (133-615): 1.75e-112: 374: 22.92
+	Hs
		62292 MTMR2_HUMAN (5-539): 0: 714: 36.31		MTMRB_HUMAN (17-497): 1.64e-114: 360: 19.96