HitPredict - High confidence protein-protein interactions

Interactor 1: TRIB1 (Q96RU8)
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)
Gene: TRIB1

Interactor 2: TRIB1 (Q96RU8)
Tribbles homolog 1 (TRB-1) (G-protein-coupled receptor-induced gene 2 protein) (GIG-2) (SKIP1)
Gene: TRIB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Interacting Pfam domains	Pkinase~Pkinase
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0004860 - protein kinase inhibitor activity GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol and 17 others more... GO:0014912 - negative regulation of smooth muscle cell migration GO:0019901 - protein kinase binding GO:0031434 - mitogen-activated protein kinase kinase binding GO:0031625 - ubiquitin protein ligase binding GO:0031665 - negative regulation of lipopolysaccharide-mediated signaling pathway GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032496 - response to lipopolysaccharide GO:0043405 - regulation of MAP kinase activity GO:0043409 - negative regulation of MAPK cascade GO:0045645 - positive regulation of eosinophil differentiation GO:0045651 - positive regulation of macrophage differentiation GO:0045659 - negative regulation of neutrophil differentiation GO:0046329 - negative regulation of JNK cascade GO:0048662 - negative regulation of smooth muscle cell proliferation GO:0055106 - ubiquitin-protein transferase regulator activity GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0140416 - transcription regulator inhibitor activity
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1	372
Hs

1	372

Service provided by Combinatics, Japan

Last updated: 11Aug2025