HitPredict

Interactor 1: TCPH (Q99832)
T-complex protein 1 subunit eta (TCP-1-eta) (EC 3.6.1.-) (CCT-eta) (Chaperonin containing T-complex polypeptide 1 subunit 7) (HIV-1 Nef-interacting protein) [Cleaved into: T-complex protein 1 subunit eta, N-terminally processed]
Gene: CCT7

Interactor 2: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 543 Hs			1 305
+	Hs
		1407594 TCPH_HUMAN (1-543): 0: 647: 100.00		NLE1_HUMAN (7-304): 8.2e-91: 279: 21.61
+	Hs
		882149 TCPG_HUMAN (1-541): 0: 577: 31.09		SKI8_HUMAN (1-305): 9.09e-102: 301: 100.00
+	Hs
		845257 TCPG_HUMAN (1-541): 0: 577: 31.09		LIS1_HUMAN (2-262): 1.72e-86: 266: 20.64
+	Hs
		965190 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		882075 TCPG_HUMAN (1-541): 0: 577: 31.09		FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30
+	Hs
		1291941 TCPH_HUMAN (1-543): 0: 647: 100.00		WDR5B_HUMAN (179-304): 8.24e-38: 138: 30.95
+	Hs
		1334162 TCPH_HUMAN (1-543): 0: 647: 100.00		POC1A_HUMAN (2-133): 1.59e-33: 128: 20.46
+	Hs
		876112 TCPE_HUMAN (3-527): 0: 557: 29.59		SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42
+	Hs
		1407542 TCPH_HUMAN (1-543): 0: 647: 100.00		KTNB1_HUMAN (121-302): 2.4e-16: 81.3: 27.47
+	Hs
		881861 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		209325 TCPH_HUMAN (1-543): 0: 647: 100.00		PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68
+	Hs
		882014 TCPG_HUMAN (1-541): 0: 577: 31.09		WDR5B_HUMAN (179-304): 8.24e-38: 138: 30.95
+	Hs
		882038 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1A_HUMAN (2-133): 1.59e-33: 128: 20.46
+	Hs
		875898 TCPE_HUMAN (3-527): 0: 557: 29.59		WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33
+	Hs
		876070 TCPE_HUMAN (3-527): 0: 557: 29.59		POC1A_HUMAN (2-133): 1.59e-33: 128: 20.46
+	Hs
		882051 TCPG_HUMAN (1-541): 0: 577: 31.09		POC1B_HUMAN (2-121): 1.9e-19: 90: 15.86
+	Hs
		209218 TCPG_HUMAN (1-541): 0: 577: 31.09		PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68
+	Hs
		876081 TCPE_HUMAN (3-527): 0: 557: 29.59		POC1B_HUMAN (2-121): 1.9e-19: 90: 15.86
+	Hs
		876151 TCPE_HUMAN (3-527): 0: 557: 29.59		KTNB1_HUMAN (121-302): 2.4e-16: 81.3: 27.47
+	Hs
		209216 TCPE_HUMAN (3-527): 0: 557: 29.59		PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68