HitPredict

Interactor 1: H2B1L (Q99880)
Histone H2B type 1-L (Histone H2B.c) (H2B/c)
Gene: H2BC13

Interactor 2: HDAC6 (Q9UBN7)
Protein deacetylase HDAC6 (EC 3.5.1.-) (E3 ubiquitin-protein ligase HDAC6) (EC 2.3.2.-) (Tubulin-lysine deacetylase HDAC6) (EC 3.5.1.-)
Gene: HDAC6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30009671
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Hist_deacetyl~Histone
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 126 Hs			1 1215
+	Hs
		1408039 H2B1M_HUMAN (1-126): 2.05e-54: 168: 95.24		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		257009 H2B1K_HUMAN (1-126): 4.52e-54: 167: 97.62		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		755016 H2B1B_HUMAN (1-126): 6.01e-54: 166: 96.03		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		946899 H2B1D_HUMAN (1-126): 1.28e-53: 166: 97.62		HDAC6_HUMAN (1-1215): 0: 1440: 100.00
+	Hs
		1109772 H2B2E_HUMAN (1-126): 2.17e-54: 168: 97.62		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		980745 H2B1C_HUMAN (1-126): 4.42e-54: 167: 98.41		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		754833 H2B1B_HUMAN (1-126): 6.01e-54: 166: 96.03		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		1109889 H2B3B_HUMAN (1-126): 6.19e-52: 161: 95.24		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		1109968 H2B1A_HUMAN (1-126): 1.3e-46: 148: 85.04		HDAC1_HUMAN (80-482): 4.66e-166: 503: 20.71
+	Hs
		1163105 H2B2E_HUMAN (1-126): 2.17e-54: 168: 97.62		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		1368085 H2B1M_HUMAN (1-126): 2.05e-54: 168: 95.24		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		754926 H2B1B_HUMAN (1-126): 6.01e-54: 166: 96.03		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		1368086 H2B1L_HUMAN (1-126): 3.04e-53: 164: 100.00		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		1323945 H2B3B_HUMAN (1-126): 6.19e-52: 161: 95.24		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		257017 H2B1K_HUMAN (1-126): 4.52e-54: 167: 97.62		HDAC5_HUMAN (33-471): 8.24e-146: 471: 32.48
+	Hs
		1368037 H2B1A_HUMAN (1-126): 1.3e-46: 148: 85.04		HDAC2_HUMAN (78-489): 3.62e-158: 483: 20.74
+	Hs
		188336 H2B1A_HUMAN (1-126): 1.3e-46: 148: 85.04		HDAC3_HUMAN (479-890): 1.13e-146: 450: 18.29
+	Sc
		381589 H2B2_YEAST (5-125): 1.24e-35: 120: 71.90		HDA1_YEAST (80-456): 5.08e-148: 464: 33.17