HitPredict

Interactor 1: PINK1 (Q99MQ3)
Serine/threonine-protein kinase PINK1, mitochondrial (EC 2.7.11.1) (BRPK) (PTEN-induced putative kinase protein 1)
Gene: PINK1

Interactor 2: PRKN (Q9WVS6)
E3 ubiquitin-protein ligase parkin (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase)
Gene: PRKN

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 29899409
Identification Methods anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Pkinase~ubiquitin
Common GO terms GO:0000422 - autophagy of mitochondrion
GO:0000423 - mitophagy
GO:0005634 - nucleus
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
and 20 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 580
Mm

1 464
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Rn
+ At
+ At
+ Hs
+ Sc

Service provided by Combinatics, Japan

Last updated: 11Aug2025