HitPredict

Interactor 1: NDEL1 (Q9GZM8)
Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1)
Gene: NDEL1

Interactor 2: MTCL1 (Q9Y4B5)
Microtubule cross-linking factor 1 (Coiled-coil domain-containing protein 165) (PAR-1-interacting protein) (SOGA family member 2)
Gene: MTCL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0007059 - chromosome segregation GO:0008017 - microtubule binding
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 345 Hs			1 1905
+	Hs
		1216297 CYTSA_HUMAN (2-331): 7.4e-23: 102: 16.06		MTCL3_HUMAN (7-894): 1.9e-88: 313: 42.06
+	Hs
		1191479 NDEL1_HUMAN (1-345): 1.81e-67: 217: 100.00		GRDN_HUMAN (309-722): 1.57e-14: 81.9: 20.40
+	Hs
		157026 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		MYH11_HUMAN (125-1042): 1.46e-29: 131: 8.46
+	Hs
		773112 MYH11_HUMAN (2-223): 2.18e-26: 112: 18.92		MYH10_HUMAN (115-930): 6.88e-23: 109: 10.92
+	Hs
		157021 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		MYH10_HUMAN (115-930): 6.88e-23: 109: 10.92
+	Hs
		772645 MYH9_HUMAN (2-223): 7.52e-24: 105: 17.57		MYH10_HUMAN (115-930): 6.88e-23: 109: 10.92
+	Hs
		773110 MYH10_HUMAN (2-228): 6.19e-23: 102: 18.06		MYH10_HUMAN (115-930): 6.88e-23: 109: 10.92
+	Hs
		772647 MYH11_HUMAN (2-223): 2.18e-26: 112: 18.92		MYH9_HUMAN (1054-1551): 1.52e-15: 85.5: 10.67
+	Hs
		157020 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		MYH9_HUMAN (1054-1551): 1.52e-15: 85.5: 10.67
+	Hs
		772644 MYH9_HUMAN (2-223): 7.52e-24: 105: 17.57		MYH9_HUMAN (1054-1551): 1.52e-15: 85.5: 10.67
+	Hs
		772855 CYTSA_HUMAN (2-331): 7.4e-23: 102: 16.06		MYH9_HUMAN (1054-1551): 1.52e-15: 85.5: 10.67
+	Hs
		556902 MYH9_HUMAN (2-223): 7.52e-24: 105: 17.57		MYH7_HUMAN (149-689): 1.09e-14: 82.4: 12.09
+	Hs
		156919 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		DESP_HUMAN (294-843): 6.24e-12: 73.4: 16.70
+	Hs
		157401 CTRO_HUMAN (12-211): 2.56e-24: 106: 19.32		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15
+	Hs
		772814 MYH9_HUMAN (2-223): 7.52e-24: 105: 17.57		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15
+	Hs
		1143246 KIFC1_HUMAN (12-245): 7.03e-23: 101: 16.24		PLEC_HUMAN (321-1278): 1.45e-09: 65.7: 16.15
+	Hs
		772878 MYH14_HUMAN (2-216): 1.79e-13: 73.5: 19.54		MYH9_HUMAN (1054-1551): 1.52e-15: 85.5: 10.67