HitPredict

Interactor 1: SKI8 (Q9GZS3)
Superkiller complex protein 8 (Ski8) (Meiotic recombination REC14 protein homolog) (WD repeat-containing protein 61) [Cleaved into: Superkiller complex protein 8, N-terminally processed (WD repeat-containing protein 61, N-terminally processed)]
Gene: SKIC8

Interactor 2: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.-) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	1.00	0.691

Property	Details
Experiments	36950384
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Helicase_C~WD40, SNF2-rel_dom~WD40
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016055 - Wnt signaling pathway
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 305 Hs			1 2581
+	Hs
		965260 WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33		CHD8_HUMAN (1-2581): 0: 2337: 100.00
+	Hs
		1088581 NLE1_HUMAN (7-304): 8.2e-91: 279: 21.61		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1088500 SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1132879 FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		964955 WDR5_HUMAN (179-304): 2.51e-41: 147: 33.33		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		703359 FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30		SMCA1_HUMAN (693-1705): 0: 899: 26.63
+	Hs
		209257 PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		703360 SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42		SMCA1_HUMAN (693-1705): 0: 899: 26.63
+	Hs
		1088619 WDR3_HUMAN (6-218): 4.84e-10: 62.4: 25.56		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		1085649 TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93		CHD3_HUMAN (380-2065): 0: 1026: 23.32
+	Hs
		209266 PRP4_HUMAN (218-304): 3.01e-14: 74.6: 13.68		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1133049 WDR3_HUMAN (6-218): 4.84e-10: 62.4: 25.56		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		1085655 TBL3_HUMAN (151-265): 1.22e-09: 61.2: 28.93		CHD4_HUMAN (500-2065): 0: 998: 23.41
+	Hs
		903450 FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30		SMCA4_HUMAN (69-1478): 0: 816: 23.14
+	Hs
		160120 FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30		CHD1_HUMAN (513-1808): 0: 800: 26.81
+	Hs
		903453 SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42		SMCA4_HUMAN (69-1478): 0: 816: 23.14
+	Hs
		160123 SNR40_HUMAN (2-216): 1.1e-59: 195: 22.42		CHD1_HUMAN (513-1808): 0: 800: 26.81
+	Hs
		1350646 FBXW7_HUMAN (91-303): 7.84e-64: 215: 24.30		CHD6_HUMAN (1345-2489): 5.11e-106: 383: 13.93