Interactor 1: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.-) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8
Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25515538 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Helicase_C~WD40, SNF2-rel_dom~WD40 |
| Common GO terms | GO:0005634 - nucleus GO:0016055 - Wnt signaling pathway GO:0045893 - positive regulation of DNA-templated transcription |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025