Interactor 1: CHD8 (Q9HCK8)
Chromodomain-helicase-DNA-binding protein 8 (CHD-8) (EC 3.6.4.-) (ATP-dependent helicase CHD8) (Helicase with SNF2 domain 1)
Gene: CHD8

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 25515538
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Helicase_C~WD40, SNF2-rel_dom~WD40
Common GO terms GO:0005634 - nucleus
GO:0016055 - Wnt signaling pathway
GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 2581
Hs

1 542
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Last updated: 11Aug2025