HitPredict

Interactor 1: O01963 (O01963)
RBR-type E3 ubiquitin transferase (EC 2.3.2.31)
Gene: ari-1.3

Interactor 2: UBC18 (Q21633)
Ubiquitin-conjugating enzyme E2 ubc-18 (EC 2.3.2.23)
Gene: ubc-18

Species: Caenorhabditis elegans

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	16457801
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006511 - ubiquitin-dependent protein catabolic process GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 491 Ce			1 153
+	Ce
		145380 ARI11_CAEEL (1-491): 0: 589: 75.91		UBC18_CAEEL (1-153): 3.19e-72: 215: 100.00
+	Ce
		145378 O01964_CAEEL (1-491): 0: 569: 73.44		UBC18_CAEEL (1-153): 3.19e-72: 215: 100.00
+	Ce
		1170315 Q9NA31_CAEEL (1-491): 0: 534: 58.80		UBC18_CAEEL (1-153): 3.19e-72: 215: 100.00
+	Hs
		906836 ARI1_HUMAN (43-491): 0: 522: 50.33		UB2D1_HUMAN (2-149): 1.66e-75: 223: 36.91
+	Hs
		957255 ARI1_HUMAN (43-491): 0: 522: 50.33		UB2D3_HUMAN (2-149): 5.92e-74: 219: 35.57
+	Dm
		1266993 ARI1_DROME (1-491): 0: 533: 47.32		UBC10_DROME (1-152): 8.98e-69: 206: 59.87
+	Hs
		1397308 ARI1_HUMAN (43-491): 0: 522: 50.33		UB2E2_HUMAN (2-148): 1.09e-69: 210: 31.08
+	Hs
		996048 ARI1_HUMAN (43-491): 0: 522: 50.33		UB2L3_HUMAN (1-152): 5.52e-66: 199: 59.21
+	Mm
		996058 ARI1_MOUSE (43-491): 0: 522: 50.33		UB2L3_MOUSE (1-152): 5.52e-66: 199: 59.21
+	Ce
		92410 D3NQB4_CAEEL (60-491): 1.18e-176: 504: 61.91		UBC18_CAEEL (1-153): 3.19e-72: 215: 100.00
+	Hs
		957876 ARI1_HUMAN (43-491): 0: 522: 50.33		UBE2N_HUMAN (4-148): 8.42e-65: 196: 35.62
+	Dm
		1266994 Q9VT94_DROME (1-491): 4.16e-177: 508: 43.50		UBC10_DROME (1-152): 8.98e-69: 206: 59.87
+	Hs
		335040 ARI2_HUMAN (6-480): 7.53e-153: 446: 33.13		UB2D1_HUMAN (2-149): 1.66e-75: 223: 36.91
+	Hs
		335073 ARI2_HUMAN (6-480): 7.53e-153: 446: 33.13		UB2D2_HUMAN (2-149): 4.61e-75: 222: 36.24
+	Hs
		335048 ARI2_HUMAN (6-480): 7.53e-153: 446: 33.13		UB2D3_HUMAN (2-149): 5.92e-74: 219: 35.57
+	Hs
		168583 ARI1_HUMAN (43-491): 0: 522: 50.33		UB2L6_HUMAN (1-152): 2.02e-42: 139: 47.37
+	Hs
		335042 ARI2_HUMAN (6-480): 7.53e-153: 446: 33.13		UB2E1_HUMAN (2-148): 6.19e-68: 205: 31.08
+	Hs
		335086 ARI2_HUMAN (6-480): 7.53e-153: 446: 33.13		UB2L3_HUMAN (1-152): 5.52e-66: 199: 59.21
+	Hs
		335049 ARI2_HUMAN (6-480): 7.53e-153: 446: 33.13		UBE2N_HUMAN (4-148): 8.42e-65: 196: 35.62
+	Hs
		168483 ARI2_HUMAN (6-480): 7.53e-153: 446: 33.13		UB2L6_HUMAN (1-152): 2.02e-42: 139: 47.37