Interactor 1: DHE3 (P00367)
Glutamate dehydrogenase 1, mitochondrial (GDH 1) (EC 1.4.1.3)
Gene: GLUD1

Interactor 2: DHE4 (P49448)
Glutamate dehydrogenase 2, mitochondrial (GDH 2) (EC 1.4.1.3)
Gene: GLUD2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 1.00 0.848

The method score is based on:

Property Details
Experiments 26186194, 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains ELFV_dehydrog~ELFV_dehydrog, ELFV_dehydrog~ELFV_dehydrog_N, ELFV_dehydrog_N~ELFV_dehydrog_N
Common GO terms GO:0004352 - glutamate dehydrogenase (NAD+) activity
GO:0004353 - glutamate dehydrogenase [NAD(P)+] activity
GO:0004354 - glutamate dehydrogenase (NADP+) activity
GO:0005525 - GTP binding
GO:0005739 - mitochondrion
and 5 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 558
Hs

1 558
+ Bt
+ Ec
+ Sc
+ Sc
+ Sc

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Last updated: 15 Jul 2024