HitPredict

Interactor 1: STIM2 (Q9P246)
Stromal interaction molecule 2
Gene: STIM2

Interactor 2: ALK (Q9UM73)
ALK tyrosine kinase receptor (EC 2.7.10.1) (Anaplastic lymphoma kinase) (CD antigen CD246)
Gene: ALK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	35384245, 34273398
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 746 Hs			1 1620
+	Hs
		1111748 STIM1_HUMAN (21-560): 0: 823: 54.66		ALK_HUMAN (1-1620): 0: 1901: 100.00
+	Hs
		464069 STIM2_HUMAN (1-746): 0: 1192: 100.00		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		439867 STIM2_HUMAN (1-746): 0: 1192: 100.00		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465676 STIM2_HUMAN (1-746): 0: 1192: 100.00		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		1157097 STIM2_HUMAN (1-746): 0: 1192: 100.00		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		541730 STIM2_HUMAN (1-746): 0: 1192: 100.00		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07
+	Hs
		463957 STIM1_HUMAN (21-560): 0: 823: 54.66		RET_HUMAN (804-1477): 5.87e-139: 460: 23.15
+	Hs
		710828 STIM1_HUMAN (21-560): 0: 823: 54.66		EPHB2_HUMAN (938-1436): 1.28e-127: 427: 23.26
+	Hs
		179608 STIM1_HUMAN (21-560): 0: 823: 54.66		MUSK_HUMAN (983-1391): 1.78e-119: 399: 29.98
+	Hs
		477234 STIM1_HUMAN (21-560): 0: 823: 54.66		ROS1_HUMAN (1039-1461): 3.97e-112: 397: 37.75
+	Hs
		650155 STIM1_HUMAN (21-560): 0: 823: 54.66		FGFR3_HUMAN (952-1449): 2.13e-119: 397: 26.31
+	Hs
		439726 STIM1_HUMAN (21-560): 0: 823: 54.66		INSR_HUMAN (973-1436): 1e-112: 392: 34.25
+	Hs
		465513 STIM1_HUMAN (21-560): 0: 823: 54.66		IGF1R_HUMAN (1037-1385): 8.56e-111: 386: 39.77
+	Hs
		572923 STIM1_HUMAN (21-560): 0: 823: 54.66		INSRR_HUMAN (1082-1384): 2.39e-70: 262: 43.46
+	Hs
		411889 STIM1_HUMAN (21-560): 0: 823: 54.66		NTRK1_HUMAN (1111-1392): 5.08e-62: 230: 42.07
+	Hs
		1111549 STIM1_HUMAN (21-560): 0: 823: 54.66		NTRK3_HUMAN (1093-1375): 2.7e-59: 223: 39.03
+	Hs
		541472 STIM1_HUMAN (21-560): 0: 823: 54.66		FGFR1_HUMAN (1110-1403): 6.78e-55: 209: 38.07