HitPredict

Interactor 1: KLH13 (Q9P2N7)
Kelch-like protein 13 (BTB and kelch domain-containing protein 2)
Gene: KLHL13

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	33961781, 30190310
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0016567 - protein ubiquitination
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 655 Hs			1 701
+	Hs
		1454623 KLHL9_HUMAN (44-655): 0: 548: 92.81		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1452115 KLH28_HUMAN (60-634): 1.24e-147: 441: 29.26		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1235393 KLH10_HUMAN (80-651): 1.16e-144: 435: 26.60		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1454582 KLH14_HUMAN (137-638): 6.21e-111: 348: 37.72		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1247781 KLH17_HUMAN (443-649): 9.12e-49: 182: 25.60		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1247815 KLH24_HUMAN (405-647): 7.27e-40: 156: 21.95		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459087 KLH20_HUMAN (472-647): 7.87e-39: 153: 23.73		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459082 KLHL3_HUMAN (484-653): 6.38e-33: 136: 22.35		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1121548 KEAP1_HUMAN (475-647): 1.83e-32: 134: 24.28		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459091 IPP_HUMAN (487-648): 4.61e-32: 133: 22.35		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		329116 KLHL2_HUMAN (488-653): 1.68e-29: 125: 21.69		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1200022 KLH26_HUMAN (427-643): 2e-27: 119: 16.67		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1199049 KLH12_HUMAN (522-650): 3.88e-19: 93.4: 23.49		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00