HitPredict

Interactor 1: KLH24 (Q6TFL4)
Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1)
Gene: KLHL24

Interactor 2: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30190310
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 600 Hs			1 701
+	Hs
		1459087 KLH20_HUMAN (22-591): 5.88e-174: 508: 34.36		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459082 KLHL3_HUMAN (21-593): 4.82e-169: 495: 33.05		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1247781 KLH17_HUMAN (17-594): 4.31e-162: 479: 30.96		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		329116 KLHL2_HUMAN (27-593): 1.05e-160: 474: 34.77		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1454623 KLHL9_HUMAN (42-591): 5.55e-158: 468: 25.74		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1454747 KLH13_HUMAN (43-591): 6.96e-157: 466: 25.26		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1452115 KLH28_HUMAN (48-590): 9.77e-158: 465: 29.88		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459091 IPP_HUMAN (31-590): 8.87e-157: 463: 26.03		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1200022 KLH26_HUMAN (28-594): 5.33e-144: 432: 24.15		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1430059 KLH25_HUMAN (26-581): 3.75e-143: 429: 31.83		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		161311 ENC1_HUMAN (46-579): 1.43e-88: 287: 32.86		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1312883 KLHL7_HUMAN (53-525): 2.88e-65: 226: 27.26		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1121548 KEAP1_HUMAN (405-599): 1.07e-47: 178: 25.62		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1199049 KLH12_HUMAN (292-455): 3.54e-32: 132: 28.74		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1459084 KLH21_HUMAN (485-600): 1.56e-14: 78.7: 13.82		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1235393 KLH10_HUMAN (504-600): 2.14e-14: 78.3: 21.36		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00
+	Hs
		1333284 KLH23_HUMAN (305-503): 1.08e-12: 72.8: 27.96		FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00