HitPredict

Interactor 1: FXL17 (Q9UF56)
F-box/LRR-repeat protein 17 (F-box and leucine-rich repeat protein 17) (F-box only protein 13)
Gene: FBXL17

Interactor 2: IPP (Q9Y573)
Actin-binding protein IPP (Intracisternal A particle-promoted polypeptide) (IPP) (Kelch-like protein 27)
Gene: IPP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	30190310
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BTB~LRR_6
Common GO terms	GO:0005737 - cytoplasm GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 701 Hs			1 584
+	Hs
		1454747 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH13_HUMAN (4-584): 6.19e-153: 455: 24.49
+	Hs
		1454623 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLHL9_HUMAN (4-584): 1.46e-152: 453: 25.85
+	Hs
		1452115 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH28_HUMAN (19-584): 4.32e-151: 448: 32.75
+	Hs
		329116 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLHL2_HUMAN (266-484): 1.83e-46: 174: 30.63
+	Hs
		1235393 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH10_HUMAN (227-485): 9.57e-46: 172: 21.62
+	Hs
		1121548 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KEAP1_HUMAN (388-584): 9.47e-44: 166: 31.00
+	Hs
		1199049 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH12_HUMAN (9-438): 3.26e-37: 147: 18.14
+	Hs
		1459082 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLHL3_HUMAN (271-439): 3.95e-36: 144: 28.66
+	Hs
		1247781 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH17_HUMAN (232-436): 3.79e-34: 139: 23.90
+	Hs
		1459087 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH20_HUMAN (268-436): 1.67e-33: 137: 30.18
+	Hs
		1312883 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLHL7_HUMAN (410-581): 1.48e-13: 75.5: 30.06
+	Hs
		1200022 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH26_HUMAN (369-583): 2.76e-13: 74.8: 16.32
+	Hs
		1459084 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH21_HUMAN (339-584): 2.36e-13: 74.7: 24.80
+	Hs
		1430059 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH25_HUMAN (484-582): 4.65e-09: 61.3: 20.20
+	Hs
		1247815 FXL17_HUMAN (1-701): 7.66e-166: 494: 100.00		KLH24_HUMAN (212-391): 8.84e-09: 60.2: 17.13