HitPredict - High confidence protein-protein interactions

Interactor 1: SPY1 (Q9QXV9)
Protein sprouty homolog 1 (Spry-1)
Gene: Spry1

Interactor 2: SPY1 (Q9QXV9)
Protein sprouty homolog 1 (Spry-1)
Gene: Spry1

Species: Mus musculus

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	16339969
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000132 - establishment of mitotic spindle orientation GO:0001656 - metanephros development GO:0001657 - ureteric bud development GO:0001759 - organ induction GO:0005654 - nucleoplasm and 14 others more... GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0008285 - negative regulation of cell population proliferation GO:0010719 - negative regulation of epithelial to mesenchymal transition GO:0016020 - membrane GO:0030512 - negative regulation of transforming growth factor beta receptor signaling pathway GO:0040037 - negative regulation of fibroblast growth factor receptor signaling pathway GO:0046580 - negative regulation of Ras protein signal transduction GO:0051387 - negative regulation of neurotrophin TRK receptor signaling pathway GO:0060449 - bud elongation involved in lung branching GO:0060940 - epithelial to mesenchymal transition involved in cardiac fibroblast development GO:0070371 - ERK1 and ERK2 cascade GO:0070373 - negative regulation of ERK1 and ERK2 cascade GO:1902747 - negative regulation of lens fiber cell differentiation
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1	313
Mm

1	313

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Last updated: 11Aug2025