HitPredict

Interactor 1: FBXL4 (Q9UKA2)
F-box/LRR-repeat protein 4 (F-box and leucine-rich repeat protein 4) (F-box protein FBL4/FBL5)
Gene: FBXL4

Interactor 2: SGT1 (Q9Y2Z0)
Protein SGT1 homolog (Protein 40-6-3) (Sgt1) (Suppressor of G2 allele of SKP1 homolog)
Gene: SUGT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32877691, 36896912
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 621 Hs			1 365
+	Hs
		318072 FBXL4_HUMAN (1-621): 0: 541: 100.00		TOM70_HUMAN (5-278): 4.48e-12: 69.1: 10.07
+	Hs
		1459088 FXL17_HUMAN (330-621): 1.82e-25: 113: 18.31		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1313956 AMN1_HUMAN (462-615): 1.21e-19: 90.9: 19.67		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1461032 FBXL2_HUMAN (446-620): 6.52e-17: 85.4: 19.21		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1101935 SKP2_HUMAN (482-613): 1.18e-11: 69: 15.67		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1323404 FXL14_HUMAN (327-442): 5.05e-10: 64: 18.10		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		1327288 FBXL6_HUMAN (500-615): 6.66e-09: 60.9: 19.83		SGT1_HUMAN (1-365): 5.11e-88: 271: 100.00
+	Hs
		75448 B3KM70_HUMAN (446-620): 8.09e-17: 85: 19.21		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Hs
		76586 FBXL7_HUMAN (137-452): 1.08e-15: 82: 15.41		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Hs
		76520 SKP2_HUMAN (482-613): 1.18e-11: 69: 15.67		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Hs
		76555 FXL14_HUMAN (327-442): 5.05e-10: 64: 18.10		B4DYC6_HUMAN (57-365): 6.48e-64: 206: 87.06
+	Hs
		1101887 SKP2_HUMAN (482-613): 1.18e-11: 69: 15.67		Q9BPW0_HUMAN (9-249): 2.08e-39: 147: 14.69
+	Hs
		916687 FBXL6_HUMAN (500-615): 6.66e-09: 60.9: 19.83		PPP5_HUMAN (9-249): 8.46e-39: 146: 14.69
+	Hs
		1327199 FBXL6_HUMAN (500-615): 6.66e-09: 60.9: 19.83		RPAP3_HUMAN (3-129): 1.12e-26: 113: 14.17
+	Hs
		1059601 FBXL6_HUMAN (500-615): 6.66e-09: 60.9: 19.83		SPAG1_HUMAN (2-339): 1.14e-24: 107: 12.39
+	Hs
		318028 FBXL6_HUMAN (500-615): 6.66e-09: 60.9: 19.83		TOM70_HUMAN (5-278): 4.48e-12: 69.1: 10.07