HitPredict

Interactor 1: Q9V9R2 (Q9V9R2)
Cullin-2
Gene: Cul2

Interactor 2: RBX1A (Q9W5E1)
RING-box protein 1A (Regulator of cullins 1a) (dRbx1)
Gene: Roc1a

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 18698375, 15331761
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1
Common GO terms GO:0016032 - viral process
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
GO:0031462 - Cul2-RING ubiquitin ligase complex
GO:0032436 - positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 753
Dm

1 108
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Service provided by Combinatics, Japan

Last updated: 11Aug2025