HitPredict

Interactor 1: RBX1A (Q940X7)
RING-box protein 1a (At-Rbx1;1) (Protein RING of cullins 1) (RBX1-2) (RBX1a-At)
Gene: RBX1A

Interactor 2: CUL3A (Q9ZVH4)
Cullin-3A (AtCUL3a)
Gene: CUL3A

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.80	0.825

Property	Details
Experiments	15659098, 15772280, 16792691, 15749712, 15618422
Identification Methods	two hybrid, affinity chromatography technology, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Cullin~zf-rbx1, Cullin_Nedd8~zf-rbx1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 118 At			1 732
+	At
		1373853 RBX1A_ARATH (1-118): 1.6e-55: 170: 100.00		CUL3B_ARATH (1-732): 0: 916: 88.12
+	Hs
		983793 RBX1_HUMAN (21-118): 1.89e-47: 149: 88.78		CUL3_HUMAN (3-732): 0: 843: 51.64
+	Hs
		983794 RBX1_HUMAN (21-118): 1.89e-47: 149: 88.78		CUL4A_HUMAN (6-732): 0: 822: 38.75
+	Hs
		983795 RBX1_HUMAN (21-118): 1.89e-47: 149: 88.78		CUL4B_HUMAN (4-732): 0: 820: 39.18
+	Mm
		58988 RBX1_MOUSE (21-118): 1.89e-47: 149: 88.78		CUL4B_MOUSE (4-732): 0: 819: 39.32
+	Mm
		984047 RBX1_MOUSE (21-118): 1.89e-47: 149: 88.78		CUL4A_MOUSE (3-732): 0: 817: 38.04
+	Dm
		1304398 RBX1A_DROME (15-118): 1.55e-48: 152: 86.54		Q8IP45_DROME (17-732): 0: 806: 48.67
+	Dm
		1203000 RBX1A_DROME (15-118): 1.55e-48: 152: 86.54		Q5BI50_DROME (4-732): 0: 797: 40.52
+	At
		1320285 RBX1A_ARATH (1-118): 1.6e-55: 170: 100.00		CUL4_ARATH (4-732): 0: 777: 39.81
+	At
		1373851 RBX1A_ARATH (1-118): 1.6e-55: 170: 100.00		CUL1_ARATH (25-732): 0: 734: 33.78
+	Hs
		983791 RBX1_HUMAN (21-118): 1.89e-47: 149: 88.78		CUL1_HUMAN (25-732): 0: 745: 30.47
+	Mm
		984057 RBX1_MOUSE (21-118): 1.89e-47: 149: 88.78		CUL1_MOUSE (25-732): 0: 745: 30.47
+	Hs
		983792 RBX1_HUMAN (21-118): 1.89e-47: 149: 88.78		CUL2_HUMAN (25-732): 0: 705: 30.21
+	Dm
		1173437 RBX1A_DROME (15-118): 1.55e-48: 152: 86.54		CUL1_DROME (24-732): 0: 700: 29.09
+	Sp
		151340 RBX1_SCHPO (13-118): 1.06e-46: 147: 73.59		CUL1_SCHPO (28-732): 0: 682: 29.99
+	Sp
		152067 RBX1_SCHPO (13-118): 1.06e-46: 147: 73.59		CUL3_SCHPO (4-732): 0: 659: 35.36
+	Ce
		1164796 RBX1_CAEEL (13-118): 1.07e-46: 147: 76.42		CUL2_CAEEL (14-732): 0: 646: 25.22
+	Dm
		1466835 RBX1A_DROME (15-118): 1.55e-48: 152: 86.54		Q9V9R2_DROME (25-732): 0: 628: 25.56
+	Hs
		983919 RBX1_HUMAN (21-118): 1.89e-47: 149: 88.78		CUL5_HUMAN (25-732): 0: 579: 23.36
+	Ce
		1171351 RBX1_CAEEL (13-118): 1.07e-46: 147: 76.42		CUL5_CAEEL (25-732): 0: 569: 24.03