HitPredict

Interactor 1: SRS11 (Q05519)
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)
Gene: SRSF11

Interactor 2: SRS11 (Q05519)
Serine/arginine-rich splicing factor 11 (Arginine-rich 54 kDa nuclear protein) (p54) (Splicing factor, arginine/serine-rich 11)
Gene: SRSF11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.783

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	RRM_1~RRM_1
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006397 - mRNA processing GO:0008380 - RNA splicing and 1 others more... GO:0016607 - nuclear speck
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 484 Hs			1 484
+	Hs
		1154038 NIPBL_HUMAN (208-484): 1.02e-46: 176: 14.34		NIPBL_HUMAN (208-484): 1.02e-46: 176: 14.34
+	Dm
		1369904 Q9VL71_DROME (27-173): 1.3e-36: 143: 47.65		Q9VL71_DROME (27-173): 1.3e-36: 143: 47.65
+	Hs
		984066 SRS11_HUMAN (1-484): 6.69e-53: 187: 100.00		PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71
+	Mm
		533894 DNMT1_MOUSE (175-482): 2.54e-27: 118: 17.56		DNMT1_MOUSE (175-482): 2.54e-27: 118: 17.56
+	Hs
		1037791 PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71		PRP4K_HUMAN (209-451): 5.94e-11: 67.2: 19.71
+	Hs
		1264771 TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99		TITIN_HUMAN (33-483): 2.57e-10: 65.4: 8.99
+	Mm
		1351630 PCLO_MOUSE (2-451): 1.38e-09: 63.1: 10.20		PCLO_MOUSE (2-451): 1.38e-09: 63.1: 10.20
+	Dm
		113976 M9PB30_DROME (1-477): 2.69e-09: 62.3: 8.66		M9PB30_DROME (1-477): 2.69e-09: 62.3: 8.66
+	Hs
		554259 MUC1_HUMAN (8-483): 3.11e-09: 61.5: 7.85		MUC1_HUMAN (8-483): 3.11e-09: 61.5: 7.85