HitPredict

Interactor 1: CPSF6 (Q9VSH4)
Cleavage and polyadenylation specificity factor subunit 6
Gene: CPSF6

Interactor 2: Q9VUB7 (Q9VUB7)
PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein)
Gene: Ptip

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.50	0.521

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 652 Dm			1 2294
+	Dm
		674058 BRM_DROME (275-642): 1.44e-45: 176: 14.62		Q9VUB7_DROME (1209-2286): 0: 736: 100.00
+	Mm
		59402 SMCA4_MOUSE (149-630): 2.85e-41: 163: 14.66		CHD7_MOUSE (449-876): 2.96e-90: 331: 22.08
+	Hs
		903506 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		CHD7_HUMAN (449-880): 6.05e-77: 288: 21.14
+	Hs
		130641 SPT5H_HUMAN (42-262): 2.87e-09: 62.4: 14.22		CHD7_HUMAN (449-880): 6.05e-77: 288: 21.14
+	Hs
		550446 PABP1_HUMAN (79-367): 1.82e-37: 149: 13.15		CP250_HUMAN (133-1695): 2.4e-47: 190: 8.44
+	Hs
		1129605 CPSF6_HUMAN (1-556): 2.03e-35: 142: 35.89		MDC1_HUMAN (1988-2280): 2.61e-42: 173: 23.81
+	Hs
		772683 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		MYH9_HUMAN (133-1087): 2.63e-27: 124: 9.33
+	Hs
		903434 SMCA4_HUMAN (149-630): 1.5e-42: 167: 14.77		TOPB1_HUMAN (8-726): 4.73e-13: 77.5: 10.53
+	Hs
		1141931 PTN23_HUMAN (140-591): 1.62e-24: 111: 16.70		EEA1_HUMAN (826-1732): 1.56e-18: 95.2: 8.41
+	Hs
		1364232 DIDO1_HUMAN (145-650): 1.49e-27: 121: 16.67		TOPB1_HUMAN (8-726): 4.73e-13: 77.5: 10.53
+	Hs
		925734 SC24C_HUMAN (276-474): 3.53e-10: 65.5: 17.89		TOPB1_HUMAN (8-726): 4.73e-13: 77.5: 10.53
+	Mm
		1455913 PCLO_MOUSE (130-453): 5.35e-13: 75.1: 16.77		PCLO_MOUSE (180-1349): 1.09e-09: 66.6: 13.60