Interactor 1: CDK8 (Q9VT57)
Cyclin-dependent kinase 8 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division protein kinase 8) (DmCdk8) (Mediator complex subunit Cdk8) (Mediator of RNA polymerase II transcription subunit Cdk8)
Gene: CDK8

Interactor 2: MED14 (Q9W0P8)
Mediator of RNA polymerase II transcription subunit 14 (Mediator complex subunit 14) (dRGR1)
Gene: MED14

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.54 1.00 0.737

The method score is based on:

Property Details
Experiments 22036573, 38944040
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Med14~Pkinase
Common GO terms GO:0016592 - mediator complex
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 454
Dm

1 1553
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Last updated: 11Aug2025