HitPredict

Interactor 1: Q9VTY2 (Q9VTY2)
Uncharacterized protein, isoform A (EC 1.1.1.21) (Uncharacterized protein, isoform D)
Gene: Ar2

Interactor 2: Q9Y112 (Q9Y112)
BcDNA.GH10614
Gene: Akr2E3

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	Aldo_ket_red~Aldo_ket_red
Common GO terms	GO:0004032 - aldose reductase (NADPH) activity GO:0005829 - cytosol
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 317 Dm			1 316
+	Dm
		1262195 Q9VTY2_DROME (1-317): 3.63e-150: 425: 100.00		Q7JVH6_DROME (1-316): 3.2e-139: 397: 51.90
+	Hs
		238658 AK1BA_HUMAN (3-317): 3.73e-143: 408: 42.81		AK1C3_HUMAN (1-316): 1.98e-140: 401: 40.62
+	Dm
		1476892 Q9VTY2_DROME (1-317): 3.63e-150: 425: 100.00		Q9VHX4_DROME (5-316): 2.73e-133: 383: 36.73
+	Hs
		91827 AK1BA_HUMAN (3-317): 3.73e-143: 408: 42.81		AK1BF_HUMAN (7-316): 5.21e-140: 400: 42.22
+	Hs
		915021 AK1C1_HUMAN (5-317): 2.8e-140: 400: 43.48		AK1C2_HUMAN (1-316): 2.82e-141: 403: 40.31
+	Hs
		605036 AK1C4_HUMAN (2-317): 1.16e-139: 399: 43.08		AK1C2_HUMAN (1-316): 2.82e-141: 403: 40.31
+	Hs
		605037 AK1C1_HUMAN (5-317): 2.8e-140: 400: 43.48		AK1C4_HUMAN (1-316): 9.93e-141: 402: 40.92
+	Hs
		838908 AK1C1_HUMAN (5-317): 2.8e-140: 400: 43.48		AK1C3_HUMAN (1-316): 1.98e-140: 401: 40.62
+	Hs
		605035 AK1C4_HUMAN (2-317): 1.16e-139: 399: 43.08		AK1C3_HUMAN (1-316): 1.98e-140: 401: 40.62
+	Hs
		915017 AK1C2_HUMAN (5-317): 5.25e-139: 397: 43.48		AK1C2_HUMAN (1-316): 2.82e-141: 403: 40.31
+	Hs
		838904 AK1C2_HUMAN (5-317): 5.25e-139: 397: 43.48		AK1C3_HUMAN (1-316): 1.98e-140: 401: 40.62
+	Hs
		238661 AK1BA_HUMAN (3-317): 3.73e-143: 408: 42.81		AK1D1_HUMAN (1-316): 1.25e-133: 384: 40.18
+	Hs
		572705 AK1A1_HUMAN (4-317): 5.11e-141: 402: 39.69		ALDR_HUMAN (7-316): 8.66e-134: 384: 46.03
+	Hs
		908340 AK1C1_HUMAN (5-317): 2.8e-140: 400: 43.48		AK1D1_HUMAN (1-316): 1.25e-133: 384: 40.18
+	Hs
		91829 AK1BF_HUMAN (3-317): 1.18e-139: 399: 41.25		ALDR_HUMAN (7-316): 8.66e-134: 384: 46.03
+	Dm
		121341 Q9VTY2_DROME (1-317): 3.63e-150: 425: 100.00		ALDR_DROME (3-316): 9.94e-120: 349: 47.17