Interactor 1: SRC (Q9WUD9)
Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (Proto-oncogene c-Src) (pp60c-src) (p60-Src)
Gene: SRC

Interactor 2: SHAN1 (Q9WV48)
SH3 and multiple ankyrin repeat domains protein 1 (Shank1) (GKAP/SAPAP-interacting protein) (SPANK-1) (Somatostatin receptor-interacting protein) (SSTR-interacting protein) (SSTRIP) (Synamon)
Gene: Shank1

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 15483135
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~SAM_1, SH2~SH3_2, Ank_2~SH3_1, SH3_1~SH3_2
Common GO terms GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0016020 - membrane
GO:0035255 - ionotropic glutamate receptor binding
GO:0044877 - protein-containing complex binding
and 2 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 536
Rn

1 2167
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025