HitPredict

Interactor 1: CTRO (O14578)
Citron Rho-interacting kinase (CRIK) (EC 2.7.11.1) (Serine/threonine-protein kinase 21)
Gene: CIT

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31586073
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 2027 Hs			1 1356
+	Hs
		148925 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MAGI3_HUMAN (61-1272): 3.28e-32: 139: 10.65
+	Hs
		149188 CTRO_HUMAN (1-2027): 0: 1212: 100.00		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		149079 CTRO_HUMAN (1-2027): 0: 1212: 100.00		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		149084 CTRO_HUMAN (1-2027): 0: 1212: 100.00		LNX1_HUMAN (73-395): 1.66e-13: 77.4: 12.79
+	Hs
		148718 CTRO_HUMAN (1-2027): 0: 1212: 100.00		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		148800 CTRO_HUMAN (1-2027): 0: 1212: 100.00		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Rn
		92840 CTRO_RAT (1-2027): 0: 1136: 93.58		DLG4_RAT (540-699): 1e-22: 107: 27.98
+	Mm
		823534 CTRO_MOUSE (1-2027): 0: 1113: 93.68		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		1256906 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		1137888 MRCKA_HUMAN (536-1061): 4.38e-32: 139: 11.82		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Ce
		88187 WARTS_CAEEL (8-429): 1.75e-135: 449: 29.92		D3YT29_CAEEL (438-686): 2.81e-30: 131: 21.85
+	Hs
		1232910 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		LNX2_HUMAN (50-361): 6.83e-21: 101: 11.35
+	Hs
		280078 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		MPDZ_HUMAN (446-543): 1.36e-20: 101: 40.82
+	Hs
		1020225 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		1300675 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		1246440 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		990944 LATS2_HUMAN (103-400): 4.87e-58: 222: 39.26		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Mm
		936586 ROCK2_MOUSE (864-1552): 1.88e-34: 147: 10.06		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		990961 MRCKB_HUMAN (569-1070): 4.13e-33: 143: 12.04		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06