Interactor 1: ANM5 (O14744)
Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]
Gene: PRMT5
Interactor 2: WDR5 (P61964)
WD repeat-containing protein 5 (BMP2-induced 3-kb gene protein)
Gene: WDR5
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.52 | 1.00 | 0.724 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 22689669 |
| Identification Methods | affinity chromatography technology, pull down |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | PRMT5_TIM~WD40 |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0035097 - histone methyltransferase complex |
| Homologous interactions | 7 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
