HitPredict

Interactor 1: GNB5 (O14775)
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
Gene: GNB5

Interactor 2: GBG13 (Q9P2W3)
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13
Gene: GNG13

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.812

Property	Details
Experiments	11675383, 12606627
Identification Methods	pull down, affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	G-gamma~WD40
Common GO terms	GO:0005834 - heterotrimeric G-protein complex GO:0007186 - G protein-coupled receptor signaling pathway
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 395 Hs			1 67
+	Dm
		669788 GBB2_DROME (51-394): 1.66e-106: 319: 35.17		GBGE_DROME (1-67): 2.86e-25: 90.2: 41.79
+	Hs
		560892 GBB3_HUMAN (13-309): 4.32e-60: 199: 16.89		GBG13_HUMAN (1-67): 2.61e-29: 100: 100.00
+	Hs
		921070 GBB1_HUMAN (13-309): 1.75e-58: 195: 16.56		GBG13_HUMAN (1-67): 2.61e-29: 100: 100.00
+	Hs
		1334919 GBB4_HUMAN (13-309): 7.38e-58: 193: 17.88		GBG13_HUMAN (1-67): 2.61e-29: 100: 100.00
+	Ce
		105445 GBB2_CAEEL (13-308): 5.8e-58: 194: 16.12		G5ECT6_CAEEL (4-67): 1.61e-21: 80.2: 37.50
+	Ce
		105444 GBB1_CAEEL (320-395): 1.9e-10: 63.6: 17.11		G5ECT6_CAEEL (4-67): 1.61e-21: 80.2: 37.50