HitPredict

Interactor 1: TCRG1 (O14776)
Transcription elongation regulator 1 (TATA box-binding protein-associated factor 2S) (Transcription factor CA150)
Gene: TCERG1

Interactor 2: PRKN (O60260)
E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.31) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2)
Gene: PRKN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35987950
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003714 - transcription corepressor activity GO:0005634 - nucleus GO:0016607 - nuclear speck GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 1098 Hs			1 465
+	Hs
		226051 PR40A_HUMAN (342-1079): 1.36e-67: 247: 18.03		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		154883 TCRG1_HUMAN (1-1098): 2.02e-117: 391: 100.00		ARI1_HUMAN (163-464): 3.95e-74: 244: 19.67
+	Hs
		227460 MDC1_HUMAN (24-892): 5.83e-33: 141: 9.38		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		228646 WWP1_HUMAN (269-580): 3.25e-26: 118: 14.99		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		229228 PCLO_HUMAN (170-662): 4.64e-09: 63.3: 10.46		PRKN_HUMAN (1-465): 7.37e-137: 403: 100.00
+	Hs
		476576 MACF1_HUMAN (654-1094): 7.6e-76: 277: 10.49		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		476350 WWP1_HUMAN (269-580): 3.25e-26: 118: 14.99		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	Hs
		475943 OTOG_HUMAN (1-375): 3.14e-18: 93.1: 11.25		UBC_HUMAN (1-77): 1.15e-29: 124: 32.47
+	At
		1092118 Q9LIE8_ARATH (40-708): 6.19e-14: 78.8: 12.12		UBQ3_ARATH (1-77): 1.22e-30: 122: 31.17