HitPredict

Interactor 1: CLGN (O14967)
Calmegin
Gene: CLGN

Interactor 2: IGF1R (P08069)
Insulin-like growth factor 1 receptor (EC 2.7.10.1) (Insulin-like growth factor I receptor) (IGF-I receptor) (CD antigen CD221) [Cleaved into: Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain]
Gene: IGF1R

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.50	0.457

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 610 Hs			1 1367
+	Hs
		435545 CALX_HUMAN (29-610): 0: 729: 56.85		IGF1R_HUMAN (1-1367): 0: 1387: 100.00
+	Hs
		160999 CLGN_HUMAN (1-610): 0: 804: 100.00		INSR_HUMAN (32-1365): 0: 1219: 56.54
+	Hs
		411305 CALX_HUMAN (29-610): 0: 729: 56.85		INSR_HUMAN (32-1365): 0: 1219: 56.54
+	Rn
		544766 CALR_RAT (60-456): 5.09e-130: 389: 36.00		INSR_RAT (20-1365): 0: 1210: 55.45
+	Hs
		654090 CALX_HUMAN (29-610): 0: 729: 56.85		EPHA3_HUMAN (666-1311): 0: 564: 24.96
+	Hs
		654091 CALX_HUMAN (29-610): 0: 729: 56.85		EPHA8_HUMAN (655-1337): 4.83e-169: 533: 23.87
+	Hs
		160995 CLGN_HUMAN (1-610): 0: 804: 100.00		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		161008 CLGN_HUMAN (1-610): 0: 804: 100.00		FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54
+	Hs
		161071 CLGN_HUMAN (1-610): 0: 804: 100.00		NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16
+	Hs
		654899 CALX_HUMAN (29-610): 0: 729: 56.85		ALK_HUMAN (939-1304): 2.51e-75: 278: 39.12
+	Hs
		654092 CALX_HUMAN (29-610): 0: 729: 56.85		LTK_HUMAN (989-1319): 5.64e-75: 270: 40.11
+	Hs
		384315 CALX_HUMAN (29-610): 0: 729: 56.85		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61
+	Hs
		654101 CALX_HUMAN (29-610): 0: 729: 56.85		UFO_HUMAN (790-1271): 9.27e-68: 249: 32.10
+	At
		83441 CALX2_ARATH (59-539): 1.44e-137: 413: 38.45		Y1755_ARATH (494-1295): 0: 563: 16.93
+	Hs
		507869 CALX_HUMAN (29-610): 0: 729: 56.85		FGFR1_HUMAN (972-1266): 1.32e-64: 238: 39.54
+	Hs
		654370 CALX_HUMAN (29-610): 0: 729: 56.85		NTRK3_HUMAN (977-1262): 5.74e-64: 236: 39.16
+	Hs
		161016 CLGN_HUMAN (1-610): 0: 804: 100.00		ERBB3_HUMAN (15-362): 5.41e-25: 115: 18.88
+	Hs
		601814 CALX_HUMAN (29-610): 0: 729: 56.85		ERBB3_HUMAN (15-362): 5.41e-25: 115: 18.88
+	Hs
		445825 CALX_HUMAN (29-610): 0: 729: 56.85		ROS1_HUMAN (691-919): 7.36e-11: 69.4: 17.47
+	Hs
		384313 CALR_HUMAN (60-456): 2.91e-129: 387: 36.00		NTRK1_HUMAN (977-1262): 3.02e-70: 254: 42.61