HitPredict

Interactor 1: ADA10 (O14672)
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Gene: ADAM10

Interactor 2: TEN3 (Q9P273)
Teneurin-3 (Ten-3) (Protein Odd Oz/ten-m homolog 3) (Tenascin-M3) (Ten-m3) (Teneurin transmembrane protein 3)
Gene: TENM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26686862
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0030424 - axon GO:0042803 - protein homodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 748 Hs			1 2699
+	Hs
		1047773 ATS1_HUMAN (51-659): 2.24e-151: 467: 15.75		NOTC2_HUMAN (28-698): 3.1e-27: 124: 11.14
+	Hs
		1047657 ATS15_HUMAN (1-659): 5.66e-151: 466: 15.91		NOTC2_HUMAN (28-698): 3.1e-27: 124: 11.14
+	Hs
		1008012 ADA17_HUMAN (17-647): 2.76e-132: 413: 27.90		JAG1_HUMAN (146-724): 1.22e-41: 171: 11.67
+	Hs
		1047765 ATS9_HUMAN (10-659): 5.43e-139: 452: 14.34		NOTC2_HUMAN (28-698): 3.1e-27: 124: 11.14
+	Hs
		946232 ATS12_HUMAN (18-658): 2.35e-133: 433: 13.96		NOTC2_HUMAN (28-698): 3.1e-27: 124: 11.14
+	Hs
		1047656 ATS17_HUMAN (56-659): 1.19e-126: 406: 16.42		NOTC2_HUMAN (28-698): 3.1e-27: 124: 11.14
+	Hs
		1419459 ADA33_HUMAN (77-631): 2.2e-116: 371: 19.79		NOTC3_HUMAN (118-646): 1.96e-10: 69.1: 9.68
+	Hs
		1461072 ADA30_HUMAN (36-597): 5.06e-80: 274: 19.58		JAG2_HUMAN (142-641): 5.47e-19: 96.9: 11.26
+	Hs
		1349414 ADA32_HUMAN (58-597): 3.03e-73: 255: 18.13		JAG2_HUMAN (142-641): 5.47e-19: 96.9: 11.26
+	Hs
		1349413 ADA32_HUMAN (58-597): 3.03e-73: 255: 18.13		NOTC3_HUMAN (118-646): 1.96e-10: 69.1: 9.68
+	Dm
		451809 Q94902_DROME (23-143): 1.09e-20: 99.9: 42.15		NOTCH_DROME (93-853): 3.3e-54: 213: 13.66
+	Dm
		451885 Q9VJW9_DROME (23-143): 1.08e-20: 99.9: 42.15		NOTCH_DROME (93-853): 3.3e-54: 213: 13.66
+	Dm
		262958 Q9VAI2_DROME (1-219): 3.1e-29: 127: 23.93		TENM_DROME (311-618): 1.52e-27: 125: 13.33
+	Dm
		263067 Q9VJW9_DROME (23-143): 1.08e-20: 99.9: 42.15		TENM_DROME (311-618): 1.52e-27: 125: 13.33
+	Dm
		517427 Q94902_DROME (23-143): 1.09e-20: 99.9: 42.15		DL_DROME (431-579): 7.36e-15: 83.3: 17.28
+	Dm
		517435 Q9VJW9_DROME (23-143): 1.08e-20: 99.9: 42.15		DL_DROME (431-579): 7.36e-15: 83.3: 17.28
+	Dm
		1478787 Q9VJW9_DROME (23-143): 1.08e-20: 99.9: 42.15		TENA_DROME (195-513): 1.28e-11: 73: 6.88