HitPredict

Interactor 1: XPO1 (O14980)
Exportin-1 (Exp1) (Chromosome region maintenance 1 protein homolog)
Gene: XPO1

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005635 - nuclear envelope GO:0005654 - nucleoplasm GO:0016020 - membrane GO:0031965 - nuclear membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1071 Hs			1 586
+	Hs
		162349 XPO1_HUMAN (1-1071): 0: 1022: 100.00		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Xl
		624256 Q6NS03_XENLA (1-1071): 0: 1007: 97.01		VIM1_XENLA (26-416): 6.12e-29: 121: 26.34
+	Mm
		821718 TNPO1_MOUSE (33-1045): 2.18e-132: 425: 13.94		LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37
+	Hs
		297182 IPO13_HUMAN (17-1029): 3.79e-133: 429: 16.03		K2C73_HUMAN (2-391): 1.07e-53: 193: 19.70
+	Hs
		155504 TNPO2_HUMAN (33-1045): 7.78e-129: 415: 14.41		K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61
+	Hs
		207863 XPOT_HUMAN (29-1023): 3.55e-126: 410: 14.85		K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61
+	Hs
		595232 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Hs
		595489 TNPO3_HUMAN (24-901): 9.93e-89: 307: 14.37		LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00
+	Hs
		359948 IMB1_HUMAN (27-908): 2.89e-90: 311: 11.32		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		360583 TNPO3_HUMAN (24-901): 9.93e-89: 307: 14.37		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		318909 TNPO3_HUMAN (24-901): 9.93e-89: 307: 14.37		K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61
+	Ce
		1094232 Q8MPS6_CAEEL (989-1068): 4.7e-26: 104: 47.50		LMN1_CAEEL (28-549): 1.7e-58: 206: 32.01