HitPredict

Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.50	0.553

Property	Details
Experiments	32296183, unassigned1304
Identification Methods	two hybrid, two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 358 Hs			1 992
+	Hs
		1368735 DLG3_HUMAN (14-292): 1.13e-29: 122: 14.24		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		1150506 NHRF2_HUMAN (4-187): 1.29e-21: 95.9: 36.96		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Hs
		1215983 MAGI3_HUMAN (17-285): 1.89e-18: 88.9: 16.39		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Rn
		1021987 DLG3_RAT (1-285): 8.33e-30: 122: 14.61		DLGP4_RAT (1-992): 0: 1193: 96.17
+	Hs
		154400 DLG3_HUMAN (14-292): 1.13e-29: 122: 14.24		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Rn
		1021968 DLG3_RAT (1-285): 8.33e-30: 122: 14.61		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Rn
		312188 MAGI2_RAT (107-285): 1.56e-15: 80.1: 16.02		DLGP4_RAT (1-992): 0: 1193: 96.17
+	Mm
		999797 DLG3_MOUSE (1-285): 9.86e-30: 122: 14.61		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Rn
		1021973 NHRF3_RAT (2-143): 4.9e-20: 93.2: 30.28		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Rn
		312185 MAGI2_RAT (107-285): 1.56e-15: 80.1: 16.02		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Rn
		723871 DLG4_RAT (88-235): 2.09e-13: 73.5: 19.36		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Mm
		1353862 MPDZ_MOUSE (15-324): 2.25e-14: 76.6: 19.00		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Rn
		1021979 DLG3_RAT (1-285): 8.33e-30: 122: 14.61		DLGP2_RAT (1-992): 0: 1076: 42.21
+	Hs
		1368727 DLG3_HUMAN (14-292): 1.13e-29: 122: 14.24		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		4755 DLG3_HUMAN (14-292): 1.13e-29: 122: 14.24		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Rn
		312186 MAGI2_RAT (107-285): 1.56e-15: 80.1: 16.02		DLGP2_RAT (1-992): 0: 1076: 42.21
+	Rn
		723872 DLG4_RAT (88-235): 2.09e-13: 73.5: 19.36		DLGP2_RAT (1-992): 0: 1076: 42.21
+	Rn
		1021984 DLG3_RAT (1-285): 8.33e-30: 122: 14.61		DLGP3_RAT (1-992): 0: 962: 35.20
+	Rn
		312187 MAGI2_RAT (107-285): 1.56e-15: 80.1: 16.02		DLGP3_RAT (1-992): 0: 962: 35.20
+	Hs
		1235211 DLG3_HUMAN (14-292): 1.13e-29: 122: 14.24		Q6IS01_HUMAN (1-551): 0: 679: 43.37