HitPredict

Interactor 1: MAGI3 (Q5TCQ9)
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 (Membrane-associated guanylate kinase inverted 3) (MAGI-3)
Gene: MAGI3

Interactor 2: DLGP4 (Q9Y2H0)
Disks large-associated protein 4 (DAP-4) (PSD-95/SAP90-binding protein 4) (SAP90/PSD-95-associated protein 4) (SAPAP-4)
Gene: DLGAP4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1481 Hs			1 992
+	Hs
		1091603 DLG1_HUMAN (15-341): 1.35e-24: 114: 9.39		DLGP4_HUMAN (1-992): 0: 1252: 100.00
+	Rn
		312188 MAGI2_RAT (308-1386): 6.27e-33: 141: 12.55		DLGP4_RAT (1-992): 0: 1193: 96.17
+	Mm
		1353862 MPDZ_MOUSE (184-1376): 3.61e-46: 185: 12.87		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Hs
		154399 MAGI2_HUMAN (698-1369): 2.74e-34: 146: 15.97		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Rn
		312185 MAGI2_RAT (308-1386): 6.27e-33: 141: 12.55		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Hs
		154395 DLG1_HUMAN (15-341): 1.35e-24: 114: 9.39		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Hs
		154397 DLG2_HUMAN (12-311): 3.71e-24: 112: 12.46		DLGP1_HUMAN (1-992): 0: 1167: 46.62
+	Rn
		1021973 NHRF3_RAT (13-540): 2.54e-29: 126: 11.45		DLGP1_RAT (1-992): 0: 1152: 46.00
+	Mm
		1283515 DLG1_MOUSE (15-341): 1.74e-23: 110: 9.70		DLGP1_MOUSE (1-992): 0: 1144: 45.61
+	Rn
		312186 MAGI2_RAT (308-1386): 6.27e-33: 141: 12.55		DLGP2_RAT (1-992): 0: 1076: 42.21
+	Hs
		1288693 MAGI2_HUMAN (698-1369): 2.74e-34: 146: 15.97		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		1091587 DLG1_HUMAN (15-341): 1.35e-24: 114: 9.39		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		4753 DLG1_HUMAN (15-341): 1.35e-24: 114: 9.39		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		1152422 DLG2_HUMAN (12-311): 3.71e-24: 112: 12.46		DLGP2_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		4755 DLG3_HUMAN (13-398): 4.16e-23: 109: 8.88		A0A1B0GTN4_HUMAN (1-992): 0: 1064: 43.22
+	Hs
		350664 MAGI2_HUMAN (698-1369): 2.74e-34: 146: 15.97		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Rn
		312187 MAGI2_RAT (308-1386): 6.27e-33: 141: 12.55		DLGP3_RAT (1-992): 0: 962: 35.20
+	Hs
		350660 DLG2_HUMAN (12-311): 3.71e-24: 112: 12.46		DLGP3_HUMAN (1-992): 0: 986: 35.35
+	Hs
		1235210 MAGI2_HUMAN (698-1369): 2.74e-34: 146: 15.97		Q6IS01_HUMAN (1-551): 0: 679: 43.37
+	Hs
		1152411 DLG2_HUMAN (12-311): 3.71e-24: 112: 12.46		Q6IS01_HUMAN (1-551): 0: 679: 43.37