HitPredict

Interactor 1: IPP2C (O14990)
Protein phosphatase inhibitor 2 family member C (PPP1R2 family member B) (Protein phosphatase 1, regulatory subunit 2 pseudogene 9) (Type-1 protein phosphatase inhibitor 4) (I-4)
Gene: PPP1R2C

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	unassigned1304
Identification Methods	two hybrid array, validated two hybrid, two hybrid prey pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	IPP-2~Metallophos
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 202 Hs			1 330
+	Hs
		782714 IPP2_HUMAN (1-198): 2.15e-76: 229: 41.29		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Mm
		906370 IPP2_MOUSE (1-199): 4.42e-76: 229: 41.87		PP1A_MOUSE (1-330): 0: 614: 99.70
+	Hs
		905971 IPP2B_HUMAN (1-198): 2.44e-74: 224: 40.80		PP1A_HUMAN (1-330): 0: 614: 100.00
+	Hs
		737628 IPP2_HUMAN (1-198): 2.15e-76: 229: 41.29		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		164067 IPP2C_HUMAN (1-202): 3.99e-74: 224: 100.00		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		737869 IPP2B_HUMAN (1-198): 2.44e-74: 224: 40.80		PP1G_HUMAN (1-330): 0: 579: 90.66
+	Hs
		782715 IPP2_HUMAN (1-198): 2.15e-76: 229: 41.29		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		164069 IPP2C_HUMAN (1-202): 3.99e-74: 224: 100.00		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Hs
		906500 IPP2B_HUMAN (1-198): 2.44e-74: 224: 40.80		PP1B_HUMAN (1-330): 0: 568: 87.88
+	Dm
		65575 A8JNP7_DROME (1-158): 4.41e-49: 163: 29.11		PP11_DROME (4-330): 0: 573: 87.77
+	Dm
		65574 A8JNP7_DROME (1-158): 4.41e-49: 163: 29.11		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		65576 A8JNP7_DROME (1-158): 4.41e-49: 163: 29.11		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		65577 A8JNP7_DROME (1-158): 4.41e-49: 163: 29.11		PP13_DROME (5-304): 0: 550: 91.67
+	Dm
		819222 Q9V3C7_DROME (1-158): 2.14e-41: 140: 29.11		PP11_DROME (4-330): 0: 573: 87.77
+	Ce
		821925 Q9N537_CAEEL (45-152): 3.75e-29: 108: 26.89		GLC7B_CAEEL (3-329): 0: 588: 90.52
+	Dm
		524639 Q9V3C7_DROME (1-158): 2.14e-41: 140: 29.11		PP12_DROME (7-304): 0: 553: 93.29
+	Dm
		819290 Q9V3C7_DROME (1-158): 2.14e-41: 140: 29.11		PP1B_DROME (6-326): 0: 551: 83.49
+	Dm
		984191 Q9V3C7_DROME (1-158): 2.14e-41: 140: 29.11		PP13_DROME (5-304): 0: 550: 91.67
+	Ce
		1099877 Q9N537_CAEEL (45-152): 3.75e-29: 108: 26.89		GLC7A_CAEEL (1-320): 0: 555: 84.57