HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: PAR2 (P55085)
Proteinase-activated receptor 2 (PAR-2) (Coagulation factor II receptor-like 1) (G-protein coupled receptor 11) (Thrombin receptor-like 1) [Cleaved into: Proteinase-activated receptor 2, alternate cleaved 1; Proteinase-activated receptor 2, alternate cleaved 2]
Gene: F2RL1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 897 Hs			1 397
+	Hs
		164568 TNPO2_HUMAN (1-897): 0: 648: 100.00		GPR17_HUMAN (57-385): 5.5e-65: 213: 28.06
+	Hs
		164546 TNPO2_HUMAN (1-897): 0: 648: 100.00		LPAR6_HUMAN (81-356): 6.84e-35: 133: 30.28
+	Hs
		133215 TNPO2_HUMAN (1-897): 0: 648: 100.00		P2Y10_HUMAN (60-354): 7.97e-30: 119: 29.90
+	Hs
		189122 IPO8_HUMAN (10-847): 7.28e-87: 301: 14.44		P2RY2_HUMAN (67-394): 5.94e-79: 249: 26.71
+	Hs
		458402 IMB1_HUMAN (11-871): 4.15e-93: 315: 17.72		ADRB2_HUMAN (42-383): 4.3e-72: 232: 15.08
+	Hs
		189210 IPO8_HUMAN (10-847): 7.28e-87: 301: 14.44		P2RY8_HUMAN (61-395): 2.83e-77: 244: 34.62
+	Hs
		189134 IPO8_HUMAN (10-847): 7.28e-87: 301: 14.44		PAR2_HUMAN (1-374): 4.98e-74: 237: 100.00
+	Hs
		189118 IPO8_HUMAN (10-847): 7.28e-87: 301: 14.44		APJ_HUMAN (55-383): 1.25e-69: 225: 23.17
+	Hs
		934066 XPO2_HUMAN (3-896): 3.35e-91: 311: 13.62		GPR17_HUMAN (57-385): 5.5e-65: 213: 28.06
+	Hs
		189155 IPO8_HUMAN (10-847): 7.28e-87: 301: 14.44		GPR17_HUMAN (57-385): 5.5e-65: 213: 28.06
+	Hs
		251212 RNBP6_HUMAN (11-549): 9.88e-14: 77.7: 12.42		GPR17_HUMAN (57-385): 5.5e-65: 213: 28.06