Interactor 1: GDF8 (O14793)
Growth/differentiation factor 8 (GDF-8) (Myostatin)
Gene: MSTN
Interactor 2: GDF11 (O95390)
Growth/differentiation factor 11 (GDF-11) (Bone morphogenetic protein 11) (BMP-11)
Gene: GDF11
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 1.00 | 0.691 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | TGF_beta~TGF_beta, TGF_beta~TGFb_propeptide, TGFb_propeptide~TGFb_propeptide |
| Common GO terms | GO:0005125 - cytokine activity GO:0005615 - extracellular space GO:0008083 - growth factor activity |
| Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores 
Service provided by Combinatics, Japan
Last updated: 11Aug2025