HitPredict

Interactor 1: SR140 (O15042)
U2 snRNP-associated SURP motif-containing protein (140 kDa Ser/Arg-rich domain protein) (U2-associated protein SR140)
Gene: U2SURP

Interactor 2: ERF3A (P15170)
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (Eukaryotic peptide chain release factor subunit 3a) (eRF3a) (EC 3.6.5.-) (G1 to S phase transition protein 1 homolog)
Gene: GSPT1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1029 Hs			1 499
+	Hs
		165524 SR140_HUMAN (1-1019): 0: 701: 100.00		ERF3B_HUMAN (1-499): 0: 558: 93.79
+	Hs
		165444 SR140_HUMAN (1-1019): 0: 701: 100.00		EF1A1_HUMAN (70-498): 1.24e-175: 503: 38.29
+	Hs
		1119139 PAP1L_HUMAN (62-515): 2.4e-46: 178: 12.45		ERF3B_HUMAN (1-499): 0: 558: 93.79
+	Hs
		545846 PABP4_HUMAN (269-363): 1.28e-19: 96.2: 25.26		ERF3A_HUMAN (1-499): 0: 567: 100.00
+	Hs
		516347 PABP1_HUMAN (265-363): 6.71e-19: 93.9: 25.25		ERF3A_HUMAN (1-499): 0: 567: 100.00
+	Hs
		1031386 PABP4_HUMAN (269-363): 1.28e-19: 96.2: 25.26		ERF3B_HUMAN (1-499): 0: 558: 93.79
+	Hs
		516584 PABP1_HUMAN (265-363): 6.71e-19: 93.9: 25.25		ERF3B_HUMAN (1-499): 0: 558: 93.79
+	Sc
		368322 NAM8_YEAST (263-355): 3.66e-19: 94.2: 27.96		EF1A_YEAST (70-494): 1.07e-172: 495: 37.27
+	Sc
		367874 PUB1_YEAST (238-353): 8.06e-12: 70.7: 29.31		EF1A_YEAST (70-494): 1.07e-172: 495: 37.27
+	Sc
		402912 PUB1_YEAST (238-353): 8.06e-12: 70.7: 29.31		ERF3_YEAST (72-494): 7.68e-168: 491: 57.51