HitPredict

Interactor 1: SCAM3 (O14828)
Secretory carrier-associated membrane protein 3 (Secretory carrier membrane protein 3)
Gene: SCAMP3

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	40437099
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0015031 - protein transport GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 347 Hs			1 116
+	Hs
		165583 SCAM3_HUMAN (1-347): 7.64e-153: 434: 100.00		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78
+	Hs
		165498 SCAM3_HUMAN (1-347): 7.64e-153: 434: 100.00		VAMP5_HUMAN (28-98): 2.31e-22: 85.9: 39.44
+	Hs
		178745 SCAM1_HUMAN (4-328): 2.39e-143: 410: 54.15		VAMP7_HUMAN (3-96): 2.55e-30: 109: 31.31
+	Hs
		178784 SCAM1_HUMAN (4-328): 2.39e-143: 410: 54.15		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78
+	Hs
		178834 SCAM1_HUMAN (4-328): 2.39e-143: 410: 54.15		VAMP8_HUMAN (20-99): 1.87e-24: 90.8: 32.50
+	Hs
		178941 SCAM2_HUMAN (4-341): 1.72e-139: 400: 51.33		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78
+	Dm
		614967 Q9VXV6_DROME (1-344): 9.72e-130: 376: 42.17		SYB_DROME (1-115): 4.75e-33: 114: 51.91
+	Dm
		305599 Q9VXV6_DROME (1-344): 9.72e-130: 376: 42.17		O77434_DROME (1-112): 1.38e-24: 94.3: 20.54
+	Hs
		726 A0A087WXB0_HUMAN (40-328): 1.94e-130: 376: 55.02		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78
+	Hs
		730 A0A087WXB0_HUMAN (40-328): 1.94e-130: 376: 55.02		VAMP8_HUMAN (20-99): 1.87e-24: 90.8: 32.50
+	Hs
		278533 SCAM5_HUMAN (128-328): 2.85e-86: 261: 45.27		VAMP4_HUMAN (18-99): 3.79e-27: 98.9: 35.37
+	Hs
		1154685 SCAM5_HUMAN (128-328): 2.85e-86: 261: 45.27		VAMP3_HUMAN (26-98): 5.64e-25: 92.4: 91.78