HitPredict

Interactor 1: SCAM1 (O15126)
Secretory carrier-associated membrane protein 1 (Secretory carrier membrane protein 1)
Gene: SCAMP1

Interactor 2: VAMP8 (Q9BV40)
Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB)
Gene: VAMP8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0015031 - protein transport GO:0016020 - membrane GO:0035579 - specific granule membrane GO:0042589 - zymogen granule membrane and 1 others more... GO:0055038 - recycling endosome membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 338 Hs			1 100
+	Hs
		178745 SCAM1_HUMAN (1-338): 3.97e-161: 455: 100.00		VAMP7_HUMAN (1-100): 1.48e-26: 98.8: 38.00
+	Hs
		178784 SCAM1_HUMAN (1-338): 3.97e-161: 455: 100.00		VAMP3_HUMAN (9-79): 6.57e-24: 88.8: 36.62
+	Hs
		730 A0A087WXB0_HUMAN (1-338): 7.3e-144: 410: 92.31		VAMP8_HUMAN (1-81): 2.96e-24: 89.5: 100.00
+	Hs
		726 A0A087WXB0_HUMAN (1-338): 7.3e-144: 410: 92.31		VAMP3_HUMAN (9-79): 6.57e-24: 88.8: 36.62
+	Hs
		178941 SCAM2_HUMAN (1-336): 4.91e-141: 404: 53.39		VAMP3_HUMAN (9-79): 6.57e-24: 88.8: 36.62
+	Dm
		614967 Q9VXV6_DROME (2-332): 2.3e-120: 352: 43.93		SYB_DROME (5-95): 3.49e-30: 106: 27.47
+	Hs
		165583 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		VAMP3_HUMAN (9-79): 6.57e-24: 88.8: 36.62
+	Hs
		165564 SCAM3_HUMAN (6-315): 1.51e-123: 360: 53.56		VAMP2_HUMAN (6-82): 1.81e-23: 88: 35.07
+	Hs
		278533 SCAM5_HUMAN (118-313): 7.58e-83: 252: 47.96		VAMP4_HUMAN (7-80): 6.44e-25: 92.6: 29.73
+	Hs
		1154685 SCAM5_HUMAN (118-313): 7.58e-83: 252: 47.96		VAMP3_HUMAN (9-79): 6.57e-24: 88.8: 36.62