HitPredict

Interactor 1: LSM1 (O15116)
U6 snRNA-associated Sm-like protein LSm1 (Cancer-associated Sm-like) (Small nuclear ribonuclear CaSm)
Gene: LSM1

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	28515276, 29395067
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	GTP_EFTU~LSM
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 133 Hs			1 972
+	Hs
		321402 LSM8_HUMAN (7-95): 2.25e-31: 108: 33.33		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1064819 LSM7_HUMAN (8-89): 4.34e-27: 98.5: 29.89		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		927954 RSMN_HUMAN (6-86): 1.43e-24: 95.8: 23.86		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		912044 RUXG_HUMAN (4-79): 1.75e-25: 93.5: 30.26		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		538964 RSMB_HUMAN (6-86): 1.43e-23: 93.1: 23.86		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		68421 RUXGL_HUMAN (4-79): 1.11e-22: 86.2: 28.95		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Sp
		292950 RSMB_SCHPO (6-75): 1.7e-23: 90.4: 30.77		SN114_SCHPO (1-970): 0: 928: 54.22
+	Sp
		252592 RUXG_SCHPO (4-79): 8.96e-22: 83.9: 26.32		SN114_SCHPO (1-970): 0: 928: 54.22
+	Sc
		731738 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731728 RSMB_YEAST (7-118): 6.9e-23: 90.4: 22.14		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731731 RUXG_YEAST (4-78): 1.97e-21: 83.1: 31.17		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731750 LSM7_YEAST (8-81): 5.46e-21: 83.1: 29.27		SN114_YEAST (3-967): 0: 692: 32.82
+	Sc
		731753 LSM3_YEAST (4-87): 7.53e-21: 81.9: 23.60		SN114_YEAST (3-967): 0: 692: 32.82
+	Zm
		5855 B4FMM6_MAIZE (7-78): 2.18e-22: 85.8: 33.33		A0A1D6E4M0_MAIZE (120-924): 0: 579: 20.35
+	Sc
		810526 LSM1_YEAST (4-123): 5.07e-34: 118: 40.98		RIA1_YEAST (111-485): 9.79e-110: 367: 26.97