HitPredict

Interactor 1: RPAC1 (O15160)
DNA-directed RNA polymerases I and III subunit RPAC1 (DNA-directed RNA polymerase I subunit C) (RNA polymerases I and III subunit AC1) (AC40) (DNA-directed RNA polymerases I and III 40 kDa polypeptide) (RPA40) (RPA39) (RPC40)
Gene: POLR1C

Interactor 2: RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (A34.5) (Antisense to ERCC-1 protein) (ASE-1) (CD3-epsilon-associated protein) (CD3E-associated protein) (DNA-directed RNA polymerase I subunit G) (RNA polymerase I-associated factor PAF49)
Gene: POLR1G

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.86	1.00	0.929

Property	Details
Experiments	15226435, 28514442, 24981860, 33961781, 35271311
Identification Methods	far western blotting, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	RNA_polI_A34~RNA_pol_L
Common GO terms	GO:0001650 - fibrillar center GO:0005654 - nucleoplasm GO:0005736 - RNA polymerase I complex GO:0005829 - cytosol
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 346 Hs			1 510
+	Hs
		179542 RPB3_HUMAN (45-346): 4.01e-105: 311: 26.38		RPA34_HUMAN (1-510): 8.02e-73: 241: 100.00
+	Hs
		583478 RPB3_HUMAN (45-346): 4.01e-105: 311: 26.38		MDC1_HUMAN (88-510): 8.73e-09: 60.4: 10.54